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Indian Society for Assisted Reproduction Consensus Guidelines on Preimplantation Genetic Testing in Fertilization Clinics. | LitMetric

AI Article Synopsis

Article Abstract

Study Question: What are the good practice guidelines for Pre implantation genetic testing applicable in INDIA?

What Is Already Known: Pre-Implantation Genetic Testing (PGT) is not new in India. It is used to identify euploid embryos for transfer, thus enabling couples to achieve a healthy pregnancy. There has been a lot of controversy surrounding PGT in the international forums; most of these debates have failed to reach a consensus on whether PGT should be offered or its concerns be validated more.

Study Design Size Duration: This is the report of a 2-day consensus meeting where two moderators were assigned to a group of experts to collate information on Pre implantation genetic testing and embryo biopsy practices in INDIA. This meeting utilised surveys, available scientific evidence and personal laboratory experience into various presentations by experts on pre-decided specific topics.

Participants/materials Setting Methods: Expert professionals from ISAR representing clinical, embryological and genetic fields.

Main Results And The Role Of Chance: The report is divided into various components defining the terminologies, the various requirements, qualifications, recommendations on PGT -A,M,SR, and quality management: the report and recommendations of the expert panel reflect the discussion on each of the topics and try to lay down good practice points for labs to follow.

Limitations Reasons For Caution: The recommendations are solely based on expert opinion. Future availability of data may warrant an update of the same.

Wider Implications Of The Findings: These guidelines can help labs across the country to standardise their PGT services and improve clinical outcomes.

Study Funding/competing Interests: The consensus meeting and writing of the paper was supported by funds from CooperSurgical India.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656313PMC
http://dx.doi.org/10.4103/0974-1208.330503DOI Listing

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