Study Question: What are the good practices for the use of ADD-ON Treatments in IVF cycles in INDIA?
What Is Already Known: Add on treatments in IVF are procedures and technologies which are offered to patients in hope of improving the success rates. A lot of add on treatments exist; most of them have limited evidence and data for the Indian patient population is miniscule. These interventions may have limited effects, so it is imperative that any new technology that is offered is evaluated properly and has enough evidence to suggest that it is safe and effective.
Study Design Size Duration: This is the report of a 2-day consensus meeting where two moderators were assigned to a group of experts to collate information on Add on treatments in IVF in INDIA. This meeting utilised surveys, available scientific evidence and personal laboratory experience into various presentations by experts on pre-decided specific topics.
Participants/materials Setting Methods: Expert professionals from ISAR representing clinical and embryology fields.
Main Results And The Role Of Chance: The report is divided in various components including the health of the Offspring, the various ADD ons available to an ART center, consensus points for each technology & qualifications and trainings for embryologists, the report and recommendations of the expert panel reflect the discussion on each of the topics and try to lay down good practice points for labs to follow.
Limitations Reasons For Caution: The recommendations are solely based on expert opinion. Future availability of data may warrant an update of the same.
Wider Implications Of The Findings: These guidelines can help labs across the country to standardise their ART services and improve clinical outcomes, it will also motivate clinics to collect data and report the use of Add ons to the national registry.
Study Funding/competing Interests: The consensus meeting and writing of the paper was supported by funds from CooperSurgical India.
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http://dx.doi.org/10.4103/0974-1208.330501 | DOI Listing |
J Clin Med
January 2025
Gynecological Research Laboratory, Department of Obstetrics and Gynecology, Hillel Yaffe Medical Center, Hadera 3820302, Israel.
In this research, we retrospectively studied the influence of the IVF vs. the ICSI technique on embryo morphokinetics by means of a time-lapse incubator in fresh cycles. A total of 2645 treatment cycles resulting in ovum pick-up of 11,471 fertilized oocytes were included in the research from 2018 to 2022.
View Article and Find Full Text PDFJ Clin Med
December 2024
Global Andrology Forum, Moreland Hills, OH 44022, USA.
Hormonal factors play an essential role as an underlying causative factor of oligoasthenoteratozoospermia (OAT), and these patients can benefit from hormonal medications that modulate the hypothalamic-pituitary-gonadal axis. This review aims to outline the various medications used as hormonal therapy in treating infertile men with OAT. This manuscript focuses on essential hormonal evaluation, identifying men who would benefit from treatment, selecting the appropriate medication, determining the duration of therapy, and evaluating hormonal treatment outcomes.
View Article and Find Full Text PDFNutrients
December 2024
NICM Health Research Institute, Western Sydney University, Penrith, NSW 2751, Australia.
Background And Objectives: Nutrient supplements are commonly used to improve fertility outcomes by women with infertility trying to conceive spontaneously or utilising medically assisted reproduction (MAR). However, despite their widespread use and perceived safety, there is a lack of clear guidance on the efficacy and safety of these supplements for female infertility. The aim of this umbrella review was to identify the best available and most recent evidence on the efficacy and safety of nutrient supplements for female infertility to provide evidence-based guidance for clinicians and reproductive couples.
View Article and Find Full Text PDFDiagnostics (Basel)
December 2024
Department of Obstetrics & Gynecology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
This prospective study aims to identify the effect of the dienogest 2 mg/day and aspirin 150 mg/day combined treatment for two months before frozen ET on the assisted reproduction outcome in women with adenomyosis and recurrent implantation failure (RIF). Patients were selected based on specific criteria and divided into two groups (with and without treatment). Preimplantation biochemical parameters and ultrasonographic features (endometrial thickness, uterine peristalsis, and junctional zone thickness) were compared with pregnancy rate in a non-natural cycle frozen embryo transfer technique.
View Article and Find Full Text PDFTaiwan J Obstet Gynecol
January 2025
Reproductive Medicine Center, Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua, Taiwan; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan. Electronic address:
Objective: To evaluate the effectiveness of oocyte retrieval using a single-lumen aspiration needle compared to a double-lumen aspiration needle in IVF (in vitro fertilization) patients.
Materials And Methods: This retrospective cohort study included all IVF cycles between 1st January, 2020 and 31st December, 2022 in Changhua Christian Hospital, Taiwan. Pairwise comparisons were conducted through propensity score matching analysis at a 1:3 ratio according to patients' age, anti-Müllerian hormone levels, and body weight.
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