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Mechanism of DT-13 regulating macrophages in diabetic wound healing.
Cell Signal
December 2024
College of Chemistry and Chemical Engineering, Liaoning Normal University, Dalian 116029, China. Electronic address:
Background: Diabetes is a complex metabolic system disease, and one of the main reasons why it is difficult to heal is that macrophages cannot realize the transition from pro-inflammatory M1 phenotype to anti-inflammatory M2 phenotype. Liriope spicata Lour. is a traditional Chinese medicine.
View Article and Find Full Text PDFAn Atypical Presentation of Viral Myocarditis Masquerading as Non-ST-Elevation Myocardial Infarction (NSTEMI).
Cureus
July 2024
Internal Medicine, Creighton University School of Medicine, Phoenix, USA.
Article Synopsis
- A 47-year-old man with hypertension and obesity developed severe symptoms including back pain, migratory joint pain, dyspnea, and arm weakness, linked to Coxsackie B virus-induced myositis and myocarditis, which are uncommon for this virus.
- Initial tests showed elevated enzyme levels (CK and troponin I) raising concerns for a non-ST-elevation myocardial infarction (NSTEMI), leading to immediate heart attack treatment protocols.
- After discovering the patient's recent sore throat and potential contact with an ill family member, a viral test confirmed Coxsackie B virus infection, and the patient recovered fully with supportive care, underscoring the need for thorough viral testing in similar cases.
Hansen's disease, commonly known as leprosy, is an infectious disease caused by Mycobacterium leprae. Being rare in developed countries, it is an increasingly common imported disease due to the migratory flow from countries where it is endemic. We present the case of a 21-year-old man who went to the emergency department with complaints of additive polyarthralgia involving large joints, papules, and erythematous plaques on the limbs with bullae and central necrosis and fever with chills for one week.
View Article and Find Full Text PDFMoraxella catarrhalis Septic Arthritis Unveils Undiagnosed Systemic Lupus Erythematous in a Pediatric Patient.
Cureus
December 2023
Department of Internal Medicine and Pediatrics, The University of Tennessee Health Science Center, Memphis, USA.
Septic arthritis is uncommon in pediatric patients, who are less likely to have major risk factors such as underlying joint disease or prosthetic joints. It only rarely affects the elbow and is usually caused by Gram-positive cocci, with being the most common bacterial organism. We present the case of a 15-year-old previously healthy female who experienced new-onset monoarticular nontraumatic elbow pain and was found to have a synovial effusion growing from .
View Article and Find Full Text PDFA Case of Whipple's Disease With Concomitant Esophageal Candidiasis.
Mil Med
January 2024
Department of Gastroenterology, Naval Medical Center San Diego, San Diego, CA 92134, USA.
Whipple's Disease (WD) is a rare disease caused by the infection of Tropheryma whipplei. It can lead to immunosuppression and a multitude of effects on different organ systems, resulting in a constellation of seemingly unrelated findings. Although treatment may appear straightforward, T.
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