AI Article Synopsis
- - Bisulfite sequencing is a key method for analyzing DNA methylation, linking it to epigenetics and environmental factors, but plant studies using this technique are scarce.
- - The researchers created the EpiDiverse EWAS pipeline to enhance epigenome-wide association studies (EWAS) focused on plants.
- - The pipeline was tested on two non-model plant species, Norway spruce and valley oak, demonstrating its applicability for plant research.
Article Abstract
Bisulfite sequencing is a widely used technique for determining DNA methylation and its relationship with epigenetics, genetics, and environmental parameters. Various techniques were implemented for epigenome-wide association studies (EWAS) to reveal meaningful associations; however, there are only very few plant studies available to date. Here, we developed the EpiDiverse EWAS pipeline and tested it using two plant datasets, from (Norway spruce) and (valley oak). Hence, we present an EWAS implementation tested for non-model plant species and describe its use.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594691 | PMC |
| http://dx.doi.org/10.3390/epigenomes5020012 | DOI Listing |
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