This research examined whether professional mentoring could have a positive effect on the occupational self-efficacy of autistic performing arts professionals. We compared the outcomes of one group who received mentoring to a waitlist control group. 26 participants took part in this study: 15 autistic mentees and 11 mentors, three of whom were also autistic. The mentoring programme was well received and felt to be beneficial by the participating mentees and mentors, particularly regarding gains in mentees' occupational self-efficacy. Professional mentoring also addressed several work-oriented challenges identified by autistic performing arts professionals such as feelings of isolation in the industry and need for consultation and advice on both a professional level, and for mentees with autistic mentors, also a neurodivergent one.
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http://dx.doi.org/10.1007/s10803-021-05394-x | DOI Listing |
Gerontologist
March 2025
Research Department of Clinical, Educational and Health Psychology; University College London; London; United Kingdom.
Background And Objectives: Based on mixed findings from previous research, researchers have hypothesised autism may be a protective or risk factor for age-related cognitive decline/dementia, or that autism does not influence it (parallel ageing). To differentiate between hypotheses, longitudinal studies that account for autism underdiagnosis, are needed and lacking. This study examined if higher autistic traits in adults aged 50+ are associated with a greater risk of spatial working memory (SWM) decline, a key cognitive domain affected in both healthy aging and autism.
View Article and Find Full Text PDFInt J Dev Neurosci
April 2025
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Introduction: O'Donnell-Luria-Rodan (ODLURO) syndrome is an autosomal dominant disorder associated with KMT2E gene variants. ODLURO syndrome is characterized mainly by developmental delay, intellectual disability and macrocephaly or microcephaly; in some patients, it may manifest as autism or epilepsy.
Methods: Trio whole-exome sequencing was performed on a female infant with unexplained West syndrome and developmental regression.
Mol Autism
March 2025
Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Henan Key Laboratory of Children's Genetics and Metabolic Diseases, Henan Children's Neurodevelopment Engineering Research Center, Zhengzhou, China.
Dysfunction in social interactions is a core symptom of autism spectrum disorder (ASD). Nevertheless, the neural mechanisms underlying social deficits in ASD are poorly understood. By integrating electrophysiological, in vivo fiber photometry, viral-mediated tracing, optogenetic and pharmacological stimulation, we show reduced intrinsic excitability and hypoactivity of SOM interneurons in medial prefrontal cortex (mPFC) in Magel2-deficient mice, an established ASD model, were required to social defects.
View Article and Find Full Text PDFMol Autism
March 2025
Lurie Family Foundations MEG Imaging Center, Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
We and others have demonstrated the resting-state (RS) peak alpha frequency (PAF) as a potential clinical marker for young children with autism spectrum disorder (ASD), with previous studies observing a higher PAF in school-age children with ASD versus typically developing (TD) children, as well as an association between the RS PAF and measures of processing speed in TD but not ASD. The brain mechanisms associated with these findings are unknown. A few studies have found that in children more mature optic radiation white matter is associated with a higher PAF.
View Article and Find Full Text PDFJ Commun Disord
February 2025
University of the Basque Country (UPV/EHU), Centro de Investigación Micaela Portilla Ikergunea, Justo Vélez de Elorriaga 1, 01006 Vitoria-Gasteiz, Spain. Electronic address:
This paper compares the performance of autistic and neurotypical participants in discourse-completion tasks that require the identification of two types of particularised conversational implicature. Material implicatures are those in which the inferential relationship from what is said to the implicature can be reconstructed without recourse to descriptions of the speaker's behaviour and the reasons underlying it, while behavioural implicatures do require such descriptions. We hypothesised that autistic participants would perform on a par with neurotypical participants in the material cases, but less well than neurotypicals in the behavioural cases, given that the latter make greater demands on theory of mind.
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