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http://dx.doi.org/10.3389/fchem.2021.815071 | DOI Listing |
World J Gastroenterol
June 2024
Metabolic Dysfunction-Associated Fatty Liver Disease Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China.
Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most prevalent chronic liver condition worldwide. Current liver enzyme-based screening methods have limitations that may missed diagnoses and treatment delays. Regarding Chen , the risk of developing MAFLD remains elevated even when alanine aminotransferase levels fall within the normal range.
View Article and Find Full Text PDFBiochim Biophys Acta Proteins Proteom
May 2024
Department of Food and Drug, University of Parma, Parma, Italy; Institute of Biophysics, National Research Council, Pisa, Italy.
Methionine gamma lyase (MGL) is a bacterial and plant enzyme that catalyzes the conversion of methionine in methanthiol, 2-oxobutanoate and ammonia. The enzyme belongs to fold type I of the pyridoxal 5'-dependent family. The catalytic mechanism and the structure of wild type MGL and variants were determined in the presence of the natural substrate as well as of many sulfur-containing derivatives.
View Article and Find Full Text PDFFront Bioeng Biotechnol
August 2023
Dermatology Hospital, Southern Medical University, Guangzhou, China.
Biosensors (Basel)
April 2023
Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Enzymes constitute an extremely important class of biomacromolecules with diverse catalytic functions, which have been validated as key mediators for regulating cellular metabolism and maintaining homeostasis in living organisms [...
View Article and Find Full Text PDFBioresour Technol
November 2022
Purdue University/ Laboratory of Renewable Resources Engineering (LORRE), West Lafayette, IN, USA. Electronic address:
Liquefaction of high solid loadings of unpretreated corn stover pellets has been demonstrated with rheology of the resulting slurries enabling mixing and movement within biorefinery bioreactors. However, some forms of pelleted stover do not readily liquefy, so it is important to screen out lots of unsuitable pellets before processing is initiated. This work reports a laboratory assay that rapidly assesses whether pellets have the potential for enzyme-based liquefaction at high solids loadings.
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