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Conceptualizing a load and volume autoregulation integrated velocity model to minimize neuromuscular fatigue and maximize neuromuscular adaptations in resistance training.
Eur J Appl Physiol
January 2025
College of Kinesiology, University of Saskatchewan, Saskatoon, SK, Canada.
Resistance training (RT) load and volume are considered crucial variables to appropriately prescribe and manage for eliciting the targeted acute responses (i.e., minimizing neuromuscular fatigue) and chronic adaptations (i.
View Article and Find Full Text PDFHuman response times are governed by dual anticipatory processes with distinct neural signatures.
Commun Biol
January 2025
Department of Neuroscience, University of Pennsylvania, Philadelphia, PA, USA.
Human behavior is strongly influenced by anticipation, but the underlying neural mechanisms are poorly understood. We obtained intracranial electrocephalography (iEEG) measurements in neurosurgical patients as they performed a simple sensory-motor task with variable (short or long) foreperiod delays that affected anticipation of the cue to respond. Participants showed two forms of anticipatory response biases, distinguished by more premature false alarms (FAs) or faster response times (RTs) on long-delay trials.
View Article and Find Full Text PDFLow hysteresis and high sensitivity TPU/carbonized wood cellulose sponge sensors for monitoring dynamic pulses.
Int J Biol Macromol
January 2025
School of Textile Science and Engineering, Tiangong University, Tianjin 300387, China.
The importance of continuous and reliable pulse wave monitoring is constantly being increased in health signal monitoring and disease diagnoses. Flexible pressure sensors with high sensitivity, low hysteresis and fast response time are an effective means for monitoring pulses. Herein, a special wave-shaped layered porous structure of carbonized wood cellulose sponge (CWCS) was constructed based on natural wood (NW).
View Article and Find Full Text PDFAerobic granules extraction inhibits overgrowth of filamentous bacteria during start-up of aerobic granular sludge.
Bioresour Technol
January 2025
School of Resources and Environment, Hubei Key Laboratory of Regional Development and Environmental Response, Hubei University, Wuhan 430062, China.
In aerobic granular sludge (AGS) system, N-acyl homoserine lactones (AHLs) can effectively regulate the community structure and control filamentous bulking. It would be economically feasible to make mature granules into AHLs-rich AGS extract (AE) to replace synthesized AHLs. In this study, two SBRs were run in a fully aerobic environment and a short cycle (4 h) to culture AGS: R1 with AE adding; R2 served as control.
View Article and Find Full Text PDFBridging the gap: The endocannabinoid system as a functional fulcrum for benzodiazepines in a novel frontier of anxiety pharmacotherapy.
Pharmacol Ther
January 2025
Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Iran; Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address:
While benzodiazepines have been a mainstay of the pharmacotherapy of anxiety disorders, their short-term efficacy and risk of abuse have driven the exploration of alternative treatment approaches. The endocannabinoid (eCB) system has emerged as a key modulator of anxiety-related processes, with evidence suggesting dynamic interactions between the eCB system and the GABAergic system, the primary target of benzodiazepines. According to the existing literature, the activation of the cannabinoid receptors has been shown to exert anxiolytic effects, while their blockade or genetic deletion results in heightened anxiety-like responses.
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