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| http://dx.doi.org/10.5051/jpis.215106edi01 | DOI Listing |
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Genomic sequencing in diverse and underserved pediatric populations: parent perspectives on understanding, uncertainty, psychosocial impact, and personal utility of results.
Genet Med
January 2025
Genomics Ethics, and Translational Research Program, RTI International, Research Triangle Park, NC; Department of Translational and Applied Genomics, Kaiser Permanente Center for Health Research, Portland, OR. Electronic address:
Purpose: Limited evidence evaluates parents' perceptions of their child's clinical genomic sequencing (GS) results, particularly among individuals from medically underserved groups. Five Clinical Sequencing Evidence-Generating Research (CSER) consortium studies performed GS in children with suspected genetic conditions with high proportions of individuals from underserved groups to address this evidence gap.
Methods: Parents completed surveys of perceived understanding, personal utility, and test-related distress after GS result disclosure.
applications of porcine ocular surface tissues: Advancing eye research and alternatives to animal studies.
Histol Histopathol
January 2025
Institute for Applied Ophthalmobiology (IOBA), University of Valladolid, Valladolid, Spain.
The use of tissues of porcine origin has gained significant momentum in the scientific community due to their anatomical and physiological resemblance to human tissues. This review provides a comprehensive overview of the key biological features of porcine ocular structures, including the cornea, conjunctiva, and associated tissues, in comparison to their human counterparts. Additionally, this review outlined the ex vivo applications of these tissues in the study of different biological processes and the simulation of pathological conditions.
View Article and Find Full Text PDF[Palliative care : not wait for the end of life].
Rev Med Suisse
January 2025
Service de médecine palliative, Hôpitaux universitaires de Genève, 1211 Genève 14.
Patients with serious illnesses wish to maintain their autonomy and decide the course of their end of life. The role of healthcare professionals is to assess the patient's understanding of their illness, help them become aware of the progression of their condition, and adapt these conversations according to the patient's emotional state, while providing regular spaces for discussion. Some patients continue to have expectations that may seem unrealistic despite a limited prognosis.
View Article and Find Full Text PDFEffectiveness of mobile mindfulness training on stress, burnout, and work engagement of office workers: protocol for a randomized controlled trial.
Front Public Health
January 2025
Department of Neuropsychiatry, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Background: Work stress has a detrimental impact on individual health and corporate efficiency and productivity. Mindfulness reduces workers' stress and burnout and increases work engagement and performance. Smartphone-based interventions could be an alternative to provide customized training without geographical or economic constraints.
View Article and Find Full Text PDFEthical leadership and nurses' job performance: the mediating role of self-compassion.
Front Public Health
January 2025
Outpatient Department, The Second Affiliated Hospital of Air Force Military Medical University, Xi'an, China.
Background: Ethical leadership is crucial in nursing management, and self-compassion is increasingly recognized as a significant factor influencing nurses' job performance. Although the link between ethical leadership and nurse job performance has been established, the specific mechanisms that underlie this relationship remain unclear. Additionally, there is a paucity of research examining the potential role of self-compassion in this context.
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