The 18th century was linked to a type of skin cancer with a clear professional etiology: scrotal carcinoma in chimney sweeps. Sir Percival Pott had the merit of identifying the disease as a malignant and inexorable process and of describing its natural evolution. In this article, we present some historical aspects of such description, as well as the working environment of the main individuals affected by this cancer, who were children carrying out the work of chimney sweeps.
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Pott's puffy tumor with intracranial extension in a child with incontinentia pigmenti: case based review of the eponymous disease.
Childs Nerv Syst
November 2024
Division of Pediatric Neurosurgery, Children's Hospital of Eastern Ontario (CHEO), Rm 3359, 401 Smyth Rd, Ottawa, ON, K1H 8L1, Canada.
Article Synopsis
- Pott's puffy tumor (PPT) is a rare infection of the frontal bone, posing serious neurological risks, and has been documented in cases involving immune dysfunction like Incontinentia pigmenti (IP).
- A literature review found 12 cases of PPT linked to immune issues, with diabetes and iatrogenic immunosuppression as common causes; surgical intervention is the primary treatment.
- PPT is increasingly recognized in patients with immune suppression, necessitating prompt and effective management to ensure better health outcomes.
Scrotal cancer, chimney sweepers and Sir Percival Pott.
Clin Dermatol
June 2022
Department of Pathology, Hospital de La Reina, Ponferrada, Spain; Department of Dermatology, Hospital Universitario de A Coruña, A Coruña, Spain.
The 18th century was linked to a type of skin cancer with a clear professional etiology: scrotal carcinoma in chimney sweeps. Sir Percival Pott had the merit of identifying the disease as a malignant and inexorable process and of describing its natural evolution. In this article, we present some historical aspects of such description, as well as the working environment of the main individuals affected by this cancer, who were children carrying out the work of chimney sweeps.
View Article and Find Full Text PDFThe Toxicological Mechanisms of Environmental Soot (Black Carbon) and Carbon Black: Focus on Oxidative Stress and Inflammatory Pathways.
Front Immunol
June 2017
Department of Biological Sciences and Bioengineering (BSBE), Indian Institute of Technology Kanpur, Kanpur, India.
The environmental soot and carbon blacks (CBs) cause many diseases in humans, but their underlying mechanisms of toxicity are still poorly understood. Both are formed after the incomplete combustion of hydrocarbons but differ in their constituents and percent carbon contents. For the first time, "Sir Percival Pott" described soot as a carcinogen, which was subsequently confirmed by many others.
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