Laser cyclodestructive interventions are considered the method of choice in the treatment of refractory glaucoma. However, the traumatic nature of cyclocoagulation makes it necessary to search for more gentle methods of laser treatment. One of the possible directions is the development of laser transscleral technologies that mainly affect the uveoscleral outflow. This article presents a new technique for laser activation of scleral hydropermeability (LASH) using pulse-periodic erbium glass (Er-glass) fiber-optics laser with wave length of 1.56 μm. The article describes the parameters of laser emission and the technique of LASH, and presents the mechanism of reducing intraocular pressure associated with increased transcleral drainage of intraocular fluid by forming new pores in the sclera. The effectiveness and safety of LASH is supported by a detailed example from clinical practice. This technology has proven itself as a possible alternative to the conventional contact transcleral cyclocoagulation.
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http://dx.doi.org/10.17116/oftalma202113706182 | DOI Listing |
Alzheimers Dement
December 2024
University of Arizona, Tucson, AZ, USA.
Background: Cerebral microvascular dysfunction and nitro-oxidative stress are present in patients with Alzheimer's disease (AD) and may contribute to disease progression and severity. A pro-nitro-oxidative environment can lead to post-translational modifications of ion channels central to microvascular regulation in the brain, including the large conductance Ca-activated K channels (BK). Nitro-oxidative modulation of BK can resulting in decreased activity and vascular hyper-contractility, thus compromising neurovascular regulation.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
The Miami Project to Cure Paralysis, Miami, FL, USA.
Background: Stroke and AD patients with gut complications often present worsened neurological outcomes. The goal of this study was to examine the role of extracellular vesicle (EV)-mediated pyroptosis in the bi-directional gut-brain axis after photothrombotic stroke (PTS) in aged 3xTg mice and wildtype (WT) controls.
Method: Twelve-month 3xTg and WT male and female mice underwent PTS using a YAG laser.
Eur J Dent
December 2024
Department of Preventive and Restorative Dentistry, College of Dental Medicine, University of Sharjah, Sharjah, United Arab Emirates.
Objective: This study compares the color change of non-vital anterior teeth after laser-activated bleaching and conventional walking bleaching technique.
Materials And Methods: Sixty extracted teeth were endodontically treated, stained in a black tea solution, and the baseline shade was measured using a spectrophotometer (Easyshade, VITA). Bleaching was done using either: internal bleaching with 35% HO (Opalescence Endo) and then tooth sealed for 5 days (Gr1), 35% HO (JW Next) for 7 minutes (Gr2), internal and external bleaching for 7 minutes (Gr3), diode laser-activated internal bleaching for 30 seconds (940 nm, continuous wave, 2 W, noncontact mode, 300 um, non-initiated tip), wait for 7 minutes, second laser application for 30 seconds, tooth sealed for 5 days (Gr4), diode laser-activated internal bleaching for 24 hours (Gr5), or diode laser-activated internal and external bleaching for 24 hours (Gr6) ( = 10).
Inorg Chem
January 2025
Key Laboratory of Functional Molecular Solids, Ministry of Education, College of Chemistry and Materials Science, Anhui Normal University, Wuhu, Anhui 241002, P. R. China.
The utilization of nonlinear optical (NLO) crystals plays a crucial role in the contemporary laser industry, and the advancement of novel NLO-active units is essential for the exploration of NLO materials. Two novel organic-inorganic hybrid iodates, designated as (CNH)MoO(IO)·3HO () and (CNIH)MoO(IO)·4HO () were synthesized via mild hydrothermal methods, exhibiting band gaps of 3.75 and 3.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Mechanical Engineering, Stevens Institute of Technology, Hoboken, NJ, 07030, USA.
Two-Dimensional transition metal dichalcogenides have been the subject of extensive attention thanks to their unique properties and atomically thin structure. Because of its unprecedented room-temperature magnetic properties, iron-doped MoS (Fe:MoS) is considered the next-generation quantum and magnetic material. It is essential to understand Fe:MoS's thermal behavior since temperature and thermal load/activation are crucial for their magnetic properties and the current nano and quantum devices have been severely limited by thermal management.
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