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Factors influencing failure of progression to completion hepatectomy following liver venous deprivation procedures (PVE or DVE): a longitudinal observational study.

HPB (Oxford)

December 2024

Department of HPB Surgery and Liver Transplantation, Queen Elizabeth Hospital, Birmingham, UK; Institute of Immunology and Immunotherapy, University of Birmingham, UK. Electronic address:

Background: Two-staged hepatectomy (TSH) with portal (PVE) or dual vein embolization (DVE) gained acceptance in liver surgery. The current study assesses the incidence and causes of failure to progress to completion hepatectomy following PVE/DVE and its influence on overall survival (OS).

Methods: This is a longitudinal observational study of patients who underwent PVE or DVE between April 2010-December 2023.

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  • Prenatal exome sequencing (pES) was introduced in England to improve genetic diagnosis in fetuses with structural anomalies, and the study aimed to analyze its outcomes between October 2021 and June 2022, including diagnostic yield and referral rates.
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