AI Article Synopsis

  • The use of antibiotic-impregnated cement is effective for treating chronic osteomyelitis and works as a local antibiotic delivery system.
  • The antibiotic cement bead rouleaux technique is a quick (10 minutes) and simple method for creating antibiotic beads with common operating room supplies.
  • The discoid shape of these beads increases the surface area for antibiotic release, making it a beneficial option for surgeons.

Article Abstract

The use of antibiotic-impregnated cement as a local antibiotic delivery system is well-established as an adjunctive treatment for chronic osteomyelitis. Because the elution of antibiotics is a surface area phenomenon, the geometry of the cement is an important consideration. The antibiotic cement bead rouleaux technique is a simple and efficient method of bead fabrication that requires only 10 minutes of preparation time and readily available operating room supplies. The discoid structure of the beads provides 3 times the surface-area-to-volume ratio of a spherical bead, which facilitates antibiotic elution. Given the speed and ease of fabrication, along with optimized geometry, the antibiotic cement bead rouleaux is a useful addition to the surgeon's repertoire.

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http://dx.doi.org/10.1097/BOT.0000000000002335DOI Listing

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