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First Detection of SARS-CoV-2 Delta (B.1.617.2) Variant of Concern in a Dog with Clinical Signs in Spain. | LitMetric

AI Article Synopsis

  • A case study in Spain details the first report of a dog infected with the Delta variant of SARS-CoV-2, despite dogs being considered less susceptible to the virus.
  • The infected dog showed mild digestive and respiratory symptoms, along with a low viral load found in an oropharyngeal swab.
  • The study highlights the significance of examining how different animal species may be affected by various COVID-19 variants and their possible roles in the pandemic.

Article Abstract

Several cases of naturally infected dogs with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported despite the apparently low susceptibility of this species. Here, we document the first reported case of infection caused by the Delta (B.1.617.2) variant of concern (VOC) in a dog in Spain that lived with several household members suffering from Coronavirus Infectious Disease 2019 (COVID-19). The animal displayed mild digestive and respiratory clinical signs and had a low viral load in the oropharyngeal swab collected at the first sampling. Whole-genome sequencing indicated infection with the Delta variant, coinciding with the predominant variant during the fifth pandemic wave in Spain. The dog seroconverted, as detected 21 days after the first sampling, and developed neutralizing antibodies that cross-neutralized different SARS-CoV-2 variants. This study further emphasizes the importance of studying the susceptibility of animal species to different VOCs and their potential role as reservoirs in the context of COVID-19.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704391PMC
http://dx.doi.org/10.3390/v13122526DOI Listing

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