A method to increase the sensitivity of an intracavity differential phase measurement that is not made irrelevant by a larger increase of noise is explored. By introducing a phase velocity feedback by way of a resonant dispersive element in an active sensor in which two ultrashort pulses circulate, it is shown that the measurement sensitivity is elevated without significantly increasing the Petermann excess noise factor. This enhancement technique has considerable implications for any optical phase based measurement; from gyroscopes and accelerometers to magnetometers and optical index measurements. Here we describe the enhancement method in the context of past dispersion enhancement studies including the recent work surrounding non-Hermitian quantum mechanics, justify the method with a theoretical framework (including numerical simulations), and propose practical applications.
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http://dx.doi.org/10.3390/s21248473 | DOI Listing |
BMC Infect Dis
January 2025
Department of Disease Prevention and Control, Second Affiliated Hospital of Navy Medical University, Shanghai, China.
Background: Limited information is available regarding the changes in blood culture utilization following the COVID-19 pandemic. Blood culture utilization rate is a critical indicator of diagnostic efficiency for infectious diseases. This study aims to describe the impact of the COVID-19 pandemic on blood culture utilization rate in Shanghai.
View Article and Find Full Text PDFBMC Emerg Med
January 2025
Department of Emergency Medicine, Recep Tayyip Erdoğan University Training and Research Hospital, Rize, 53020, Turkey.
Background: The incidence of contrast-induced acute kidney injury (CI-AKI) in the general population ranges from 0.6 to 2.3%, whereas for specific high-risk patients, the incidence can reach more than 30-40%.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
January 2025
Life Sciences, Hamburg University of Applied Science, Ulmenliet 20, 21033, Hamburg, Germany.
The use of rare earth elements has increased in recent years, leading to a rise in environmental concentrations. Despite the growth in number of studies regarding toxicity, knowledge gaps remain. For Daphnia magna, standardized test methods involve exposure periods of either 48 h or 21 days to assess toxicological effects.
View Article and Find Full Text PDFIntroduction: Obesity is a worldwide epidemic, with up to 17% of French population affected. European guidelines recommend surgical management at specific weight and comorbidity level; however, less than 2% of eligible patients undergo surgical bariatric interventions. To extend the benefits of bariatric interventions to the untreated population with obesity, endoscopic techniques such as endoscopic sleeve gastroplasty (ESG) have been developed.
View Article and Find Full Text PDFNat Cancer
January 2025
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Human tumors are diverse in their natural history and response to treatment, which in part results from genetic and transcriptomic heterogeneity. In clinical practice, single-site needle biopsies are used to sample this diversity, but cancer biomarkers may be confounded by spatiogenomic heterogeneity within individual tumors. Here we investigate clonally expressed genes as a solution to the sampling bias problem by analyzing multiregion whole-exome and RNA sequencing data for 450 tumor regions from 184 patients with lung adenocarcinoma in the TRACERx study.
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