Allergic rhinitis (AR) is a chronic disease that is becoming increasingly common worldwide and has a negative impact on school performance, work performance, and quality of life. The aim of this study was to investigate the effect of vitamin D on the symptoms of AR in children. Serum vitamin D levels of children with AR and age-matched healthy controls were compared using the high-pressure liquid chromatography method. The relationship between serum vitamin D levels and symptoms and severity of AR was then examined. The study included 137 patients diagnosed with AR (76 males, 61 females; median age: 11 years). Serum vitamin D levels were lower in the patient group than in the control group ( = 0.001), lower in all aeroallergen groups (mites, pollen, and multiple inhalants) than in the healthy control group ( = 0.001), and lower in both the perennial AR group and the seasonal AR group than in the control group ( = 0.001). Spearman correlation analysis showed that there was no correlation between symptom score and vitamin D level ( = -0.099; = 0.25). We found no correlation between serum vitamin D level and symptoms and severity of AR. Serum vitamin D levels were lower in children with AR than in healthy children.
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| http://dx.doi.org/10.1089/ped.2021.0161 | DOI Listing |
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