A retrospective review of liquid mycobacterial cultures was performed at a laboratory in South Africa from 01 January 2018 to 31 December 2018 to assess the increased yield in detecting complex following sample re-decontamination. Only 9 of 99 (9%) re-decontaminated samples were culture positive for complex. Xpert MTB/RIF Ultra, concurrently performed on 7 of the 9 samples, detected complex in all but 1 sample. Re-decontamination of non-sterile samples did not increase the complex yield enough to offset the financial costs and additional labour in a laboratory that utilises the Xpert MTB/RIF Ultra system as a first-line diagnostic modality.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678946 | PMC |
| http://dx.doi.org/10.4102/ajlm.v10i1.1529 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Diagnostic accuracy of Xpert MTB/RIF Ultra for detecting pulmonary tuberculosis and rifampicin resistance: a systematic review and meta-analysis.
Eur J Clin Microbiol Infect Dis
January 2025
Department of Ultrasound Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510150, China.
Background: Public health issues related to tuberculosis still exist. Because Xpert MTB/RIF Ultra is more effective than conventional TB diagnostic techniques are, it is now regarded as an emerging technology. The diagnostic accuracy of Xpert MTB/RIF Ultra for tuberculosis was assessed in this systematic study.
View Article and Find Full Text PDFMultigene cell-free DNA assay.
Int J Tuberc Lung Dis
January 2025
Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Prevalence and factors associated with TB among presumptive TB patients in war-affected areas of North Wollo, Ethiopia.
JAC Antimicrob Resist
February 2025
Department of Medical Laboratory Science, College of Health Sciences, Woldia University, Woldia, Ethiopia.
Background: TB is a leading infectious disease globally, with war and displacement significantly increasing its burden. In Ethiopia, ongoing conflict and displacement have worsened health conditions, yet data on TB prevalence and resistance remain scarce. This study aimed to determine the prevalence of TB, rifampicin-resistant TB (RR-TB), and associated factors among presumptive TB patients in hospitals during the ongoing crisis.
View Article and Find Full Text PDFPrevalence and causes of rifampicin-resistance genotypic/phenotypic discrepancy detected on Xpert MTB/RIF in Singapore.
Ann Acad Med Singap
December 2024
National Tuberculosis Care Centre, Tan Tock Seng Hospital, Singapore.
Rapid quantitative PCR on tongue swabs for pulmonary tuberculosis in adults: a prospective multicentre study.
Eur Respir J
January 2025
Department of Bacteriology and Immunology, Beijing Chest Hospital, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China
Background: Tuberculosis (TB) remains a major cause of infectious disease mortality globally, with significant underdiagnosis perpetuating transmission. Tongue swab analysis has emerged as a promising non-invasive method for pulmonary TB diagnosis. This study evaluates the diagnostic accuracy of the TB-EASY quantitative PCR (qPCR) assay using tongue swab specimens.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!