AI Article Synopsis

  • * Treatment options for brain metastases include radiosurgery or whole-brain radiation therapy, depending on the location of the lesions and surrounding structures.
  • * A case study of a 68-year-old man from Ecuador is presented, showcasing the effective use of linear particle accelerator radiosurgery for treating dual central nervous system metastasis in a cost-effective manner in a resource-limited context.

Article Abstract

Large cell neuroendocrine carcinoma, a type of non-small cell lung cancer, is quite rare and has been associated with brain metastasis, mainly to the cerebral hemispheres. However, the rate of cerebellar metastasis is underreported in the literature and appears to be quite rare. Despite the rarity of this metastasis, treatment guidelines for both supratentorial and cerebellar lesions have been established by using either radiosurgery or whole-brain radiation therapy. The choice of modality must take into consideration the vicinity of relevant structures such as the brainstem and its multiple nuclei. Here we report the case of a 68-year-old male, resident of a rural community in the Andean region of Ecuador, a low-middle income country; with the diagnosis of a large cell neuroendocrine carcinoma of the lung with dual central nervous system metastasis treated with linear particle accelerator radio-surgery due to its versatility and cost-effectiveness in a resource-limited setting. We showcase the rarity of the metastatic lesions as well as the utility of linear accelerators and their versatility to perform precise radiosurgical procedures in two simultaneous locations.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693538PMC
http://dx.doi.org/10.7759/cureus.19806DOI Listing

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