First Report of Bacteremia Caused by in China.

Infect Drug Resist

Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China.

Published: December 2021

AI Article Synopsis

  • Bacteremia caused by a rare opportunistic agent accounts for 0.5-2% of positive blood cultures and is particularly dangerous for immunocompromised patients.
  • A 74-year-old woman with an abdominal infection and recurrent ovarian tumor underwent successful treatment after being diagnosed with this infection, confirmed through blood cultures and advanced identification techniques.
  • This case marks the first report of such bacteremia in China and highlights the importance of recognizing these infections, as well as the use of MALDI-TOF MS for identification in clinical settings.

Article Abstract

Background: Bacteremia caused by is an extremely rare infection that accounts for 0.5-2% of all positive blood cultures. is an opportunistic agent that is highly lethal in immunocompromised or epithelial barrier disruption hosts.

Case Presentation: A 74-year-old woman was admitted to our hospital with a high fever. The patient was diagnosed with an abdominal infection after a bowel invasion and recurrence of an ovarian tumor after surgery. Blood sample culturing yielded transparent, smooth, moist, slightly raised colonies without a hemolytic ring. was identified by gram staining and MALDI-TOF MS. 16S rRNA gene sequencing confirmed a sequence homologous to in the GenBank database. Drug susceptibility testing showed that was sensitive to cefoxitin, clindamycin, imipenem, meropenem, metronidazole, and vancomycin. After treatment, the patient's body temperature was normal and she was discharged from the hospital.

Conclusion: This is the first case report of bacteremia caused by in China and also the first report of identifying in clinical specimens by MALDI-TOF MS. This case study could increase the awareness of these infections in China.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692879PMC
http://dx.doi.org/10.2147/IDR.S344062DOI Listing

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