AI Article Synopsis
- Penile cancers are rare and should be managed at specialized centers, primarily using brachytherapy for early-stage glans cancer.
- Brachytherapy is effective for disease control and helps preserve the organ and its function, while data on external beam radiation therapy is limited.
- External beam radiation may be considered for palliative care or lymph node treatment, but decisions should be made individually due to insufficient evidence, following guidelines from the French Society of Oncological Radiotherapy.
Article Abstract
Penile cancers are uncommon and should be treated in expert center. Radiotherapy indications are mainly limited to exclusive brachytherapy for early stage penile glans cancer. Brachytherapy yields to excellent outcome for disease control and organ and function preservation. Only scarce data are available for external beam radiation therapy. It could be considered as palliative setting for irradiation of the primary tumor. For lymph node irradiation, external beam radiation therapy (with or without chemotherapy) could be discussed either as neoadjuvant approach prior to surgery for massive inguinal lymph node invasion or as adjuvant approach in case of high-risk of relapse. However, these cases should be discussed on an individual basis, as the level of evidence is poor. We present the recommendations of the French Society of Oncological Radiotherapy on the indications and techniques for external beam radiotherapy and brachytherapy for penile glans cancer.
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| http://dx.doi.org/10.1016/j.canrad.2021.10.001 | DOI Listing |
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