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Inverse dose protraction effects of high-LET radiation: evidence and significance.
Mutat Res Rev Mutat Res
January 2025
Radiation Epidemiology Branch, National Cancer Institute, MD 20892-9778, USA; Faculty of Health, Science and Technology, Oxford Brookes University, Headington Campus, OX3 0BP, UK.
Biological effects of ionizing radiation vary with radiation quality, which is often expressed as the amount of energy deposited per unit length, i.e., linear energy transfer (LET).
View Article and Find Full Text PDFStrategies for Improving Care of Patients with Acute Kidney Injury Requiring Dialysis (AKI-D) in the Outpatient Hemodialysis Setting.
Nephrol Nurs J
January 2025
Senior Consultant to the Global Medical Office, Fresenius Medical Care, Waltham, MA.
Patients with acute kidney injury often require dialysis (AKI-D) in the outpatient setting following hospitalization. Management of the patient with AKI-D should focus on preventing further insult to the damaged kidney and recovery of kidney function. Clinical attention should include continuity of care, education, infection control, medication management, and fluid management.
View Article and Find Full Text PDFProtective effects of Mito-TEMPO on ischemia-reperfusion injury in a mouse testicular torsion and detorsion model.
Vet Res Forum
December 2024
Department of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
Testicular ischemia-reperfusion (I/R) injury during testicular torsion is strongly influenced by oxidative stress caused by excessive accumulation of unscavenged reactive oxygen species. This study aimed to investigate the effects of intra-peritoneal administration of Mito-TEMPO (MT) on I/R injury in testicular torsion/detorsion (T/D) in mice. Forty-two male mice were divided into seven groups including 1 control and 6 treatment groups (360° T/D, 720° T/D, 360° T/D + 0.
View Article and Find Full Text PDFMarburg variant of multiple sclerosis: A young women case report.
Radiol Case Rep
March 2025
Emergency Department, Baghdad Medical City, Baghdad, Iraq.
Marburg disease (malignant multiple sclerosis, MS) is a rare, acute MS variant, predominantly occurring among young adults. Because it is characterized by rarity, high morbidity and mortality rates, the disease needs to be further characterized, and the experience of the physicians play a role in treatment regimens. We report the case of a 15-years-old female presenting with progressive weakness over the limbs, hyperreflexia and loss of sensation by physical examination, lab tests and radiological investigations (MRI).
View Article and Find Full Text PDFPharmacological validation of a novel exopolysaccharide from sp. 139 to effectively inhibit cytokine storms.
Heliyon
July 2024
NHC Key Laboratory of Biotechnology of Antibiotics, CAMS Key Laboratory of Synthetic Biology for Drug Innovation, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
With the rapid development of immunotherapy in recent years, cytokine storm has been recognized as a common adverse effect of immunotherapy. The emergence of COVID-19 has renewed global attention to it. The cytokine storm's inflammatory response results in infiltration of large amounts of monocytes/macrophages in the lungs, heart, spleen, lymph nodes, and kidneys.
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