16p11.2 copy number variations have been associated with neurodevelopmental disorders. Human induced pluripotent stem cells were generated from fibroblasts obtained from a patient diagnosed with schizophrenia with a 16p11.2 deletion. The generated cell line was further validated for its pluripotency and potential to differentiate into the three germ layers.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209596PMC
http://dx.doi.org/10.1016/j.scr.2021.102636DOI Listing

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