What Socrates drank? Comparative chemical investigation of two Greek Conium taxa exhibiting diverse chemical profiles.

Phytochemistry

Section of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, Athens, 15771, Greece. Electronic address:

Published: March 2022

AI Article Synopsis

  • - Conium divaricatum is visually different from its European counterpart, Conium maculatum, but is often debated as being the same species.
  • - A comparative study of essential oils showed that C. divaricatum contains unique hydrocarbon esters, while C. maculatum has higher levels of alkanes, alkenes, and ketones.
  • - Despite similar alkaloid levels and toxicity in testing, the differences in chemical makeup and appearance indicate that these plants should be classified as separate species.

Article Abstract

Conium divaricatum, even though exhibiting morphological differences in comparison to its congener of European origin Conium maculatum, is still considered a disputed taxon often referred to as a synonym of the latter. Herein, essential oils of various plant tissues from several populations of both taxa were comparatively investigated, showing distinct chemical profiles. In the case of C. divaricatum, the essential oils were dominated by hydrocarbon esters, among which the main constituents 4'-oxodecyl hexanoate, 4'-oxododecyl hexanoate and 4'-oxooctyl hexanoate were isolated and identified as undescribed natural products. In contrast, the essential oils of C. maculatum were dominated by hydrocarbon alkanes, alkenes and ketones, as well as the polyacetylene (Z)-falcarinol. Even though determination of the total alkaloids content and toxicity assessment against the crustacean Artemia salina did not reveal significant differences, the distinct chemical profiles and the morphological differences observed for both taxa, strongly support their distinction as separate species.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phytochem.2021.113060DOI Listing

Publication Analysis

Top Keywords

chemical profiles
12
essential oils
12
morphological differences
8
distinct chemical
8
dominated hydrocarbon
8
socrates drank?
4
drank? comparative
4
chemical
4
comparative chemical
4
chemical investigation
4

Similar Publications

The study examines the chemical composition and antimicrobial properties of petroleum ether and hydro-methanolic extracts of Achillea santolina(A. santolina)  from Algeria. Chemical profiling was performed using High-Performance Liquid Chromatography with Diode Array Detection (HPLC-DAD) for the hydro-methanolic extract and Gas Chromatography-Mass Spectrometry (GC-MS) for the petroleum ether extract.

View Article and Find Full Text PDF

GC-MS and HPLC-HRMS Metabolite Profiling and Biological Activities of Blanchetia heterotricha Extracts.

Chem Biodivers

December 2024

Universidade Federal da Bahia, Química Orgânica, Rua Professor Sabino silva 356 Ed Saint Paul, ap 502, 40155250, Salvador, BRAZIL.

Blanchetia heterotricha is a species popularly used for its medicinal properties. However, few scientific records report the investigation of its chemical composition and biological activity. Herein, a metabolomics and multivariate statistical analysis approach was used to assess the chemical composition, antioxidant, and antimicrobial activity of B.

View Article and Find Full Text PDF

Electrochemiluminescence (ECL) microscopy has emerged as a powerful technique for single-cell imaging owing to its unparalleled background-free imaging advantages. However, controlled intracellular ECL imaging remains challenging. Here, we developed a stimuli-responsive self-assembled DNA nanomachine that enables the ECL imaging of intracellular target biomolecules in single cells.

View Article and Find Full Text PDF

Giant viruses are crucial for marine ecosystem dynamics because they regulate microeukaryotic community structure, accelerate carbon and nutrient cycles, and drive the evolution of their hosts through co-evolutionary processes. Previously reported long-term observations revealed that these viruses display seasonal fluctuations in abundance. However, the underlying genetic mechanisms driving such dynamics of these viruses remain largely unknown.

View Article and Find Full Text PDF

Intra-articular glucocorticoid injections are effective in controlling inflammation and pain in arthritides but restricted by short duration of action and risk of joint degeneration. Controlled drug release using biocompatible hydrogels offers a unique solution, but limitations of in situ gelation restrict their application. Gellan sheared hydrogels (GSHs) retain the advantages of hydrogels, however their unique microstructures lend themselves to intra-articular application - capable of shear thinning under force but restructuring at rest to enhance residence.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!

A PHP Error was encountered

Severity: Notice

Message: fwrite(): Write of 34 bytes failed with errno=28 No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 272

Backtrace:

A PHP Error was encountered

Severity: Warning

Message: session_write_close(): Failed to write session data using user defined save handler. (session.save_path: /var/lib/php/sessions)

Filename: Unknown

Line Number: 0

Backtrace: