[Advances in research on chemical composition of Picrorhiza scrophulariiflora and P. kurroa and their biological activities].

Zhongguo Zhong Yao Za Zhi

State Key Laboratory of Dao-di Herbs Breeding Base, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.

Published: December 2021

AI Article Synopsis

  • A total of 141 compounds have been identified from the plants Picrorhiza scrophulariiflora and P. kurroa, categorized into various types such as iridoid glycosides and triterpenoids.
  • Pharmacological studies indicate these compounds offer protective effects on organs like the liver, heart, and brain, along with other health benefits including anti-tumor and anti-inflammatory properties.
  • The article aims to summarize existing research on the chemical components and medicinal effects of these plants, providing a foundation for further exploration and potential applications.

Article Abstract

At present, 141 compounds have been isolated from Picrorhiza scrophulariiflora and P. kurroa of the Scrophulariaceae plants, including 46 iridoid glycosides, 29 tetracyclic triterpenoids, 25 phenylpropanoids, and 11 phenylethanoid glycosides. Pharmacological studies have demonstrated that they have liver-, heart-, brain-, kidney-, and nerve cells-protecting effects as well as anti-tumor, anti-inflammatory, anti-bacterial, anti-asthma, anti-diabetic, immunomodulatory, and blood lipid-lowering activities. This article reviews the chemical components and pharmacological activities of P. scrophulariiflora and P. kurroa, aiming to provide a basis for the in-depth research, development, and utilization of the two plants.

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Source
http://dx.doi.org/10.19540/j.cnki.cjcmm.20210708.601DOI Listing

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