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Cisplatin-Induced Bradycardia: A Silent Risk Observed in Two Different Clinical Cases. | LitMetric

AI Article Synopsis

Article Abstract

Cisplatin is a platinum-containing drug that inhibits DNA synthesis by inhibiting cross-linking, denaturing DNA strands. It is used in combination with other chemotherapeutic agents to treat several types of cancers. Numerous adverse effects have been reported with this compound. However, it is considered a safe medication in terms of cardiotoxicity. In this report, we discuss the case of two patients who experienced bradycardia while receiving cisplatin as part of combination therapy. A workup was undertaken to rule out other possible causes of bradycardia, and the diagnosis of cisplatin-induced bradycardia was made.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686342PMC
http://dx.doi.org/10.7759/cureus.19769DOI Listing

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