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Opioid Overdose and Serotonin Syndrome due to Gastric Bezoar in a Woman with Autism and Pica Behaviour. | LitMetric

Opioid Overdose and Serotonin Syndrome due to Gastric Bezoar in a Woman with Autism and Pica Behaviour.

Case Rep Psychiatry

Department of Child and Adolescent Psychiatry, Reference Centre for Rare Psychiatric Diseases, Pitié-Salpêtrière Hospital, AP-HP.Sorbonne Université, 47-83 Boulevard de l'Hôpital, 75013 Paris, France.

Published: December 2021

AI Article Synopsis

Article Abstract

We are presenting the case of a 38-year-old woman with nonverbal autism and intellectual disability, hospitalized in a neurobehavioural unit because of a pica behaviour for 3 years. During the hospitalization, the patient presented an episode of pain, agitation, restlessness, rhabdomyolysis, coma, tachycardia, hyperthermia, shivering, and diarrhoea. The main hypothesis raised was tramadol overdose because of the immediate antidote response to the injection of naloxone 0,4 mg/mL. Even if we did not exceed the recommended prescription dosage of tramadol, the presence of gastric bezoar slowed the absorption of the drug, and the consequence was an opioid overdose and serotonin syndrome.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692011PMC
http://dx.doi.org/10.1155/2021/7334467DOI Listing

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