Background: During the COVID-19 pandemic, patients with immune diseases are a vulnerable population. We aimed to evaluate their access to medical care, as well as their awareness and willingness to obtain the vaccine after a year of the SARS-CoV-2 pandemic.

Methods: A cross-sectional, multicenter study was conducted on a questionnaire basis, handled both online as well as in person.

Results: 651 patients with autoimmune or immune mediated diseases were enrolled. More than half (339/641 [53%]) reported difficulties in obtaining medical care throughout the pandemic and 135/651 ([21%]) of them were confirmed with COVID-19; 442/651, ([68%]) expressed their willingness to be vaccinated against SARS-CoV-2. The factors associated with an increased probability of vaccination were the male gender (OR = 2.01, CI95% 1.2-3.7, = 0.001), the patient's opinion that she/he was well informed (OR = 3.2, CI 95% 2.1-6.01, < 0.001), physician's advice (OR = 2.1, CI 95% 1.3-3.5, < 0.001), and flu vaccination in the past (OR = 1.5, CI 95% 1.1-2.3, < 0.001), while those associated with a decreased probability of vaccination were COVID-19 disease in the past medical history (OR = 0.7, CI 95% 0.3-0.95, = 0.02), and the opinion that patients with autoimmune diseases are at increased risk for adverse reactions (OR = 0.7, CI95% 0.53-0.89, = 0.001).

Conclusions: Given the fact that considering themselves informed regarding vaccination is the most important factor in order to be immunized against SARS-CoV-2, effective information campaigns would substantially increase willingness.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700907PMC
http://dx.doi.org/10.3390/healthcare9121707DOI Listing

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