AI Article Synopsis
- The study focused on the effectiveness of vitrectomy and related treatments for macular hemorrhage due to age-related macular degeneration or retinal arterial macroaneurysm.
- A total of 65 eyes were evaluated, showing significant improvement in best-corrected visual acuity (BCVA) post-surgery, with factors like age and initial BCVA affecting outcomes.
- Results indicated that 85% of patients experienced stabilization or improvement in BCVA, highlighting the importance of younger age, better initial vision, and specific treatment strategies for optimal recovery.
Article Abstract
Objective: The study aimed to determine the outcomes and prognostic factors of vitrectomy, subretinal injection of tissue-plasminogen activator and gas tamponade in macular hemorrhage (MaH) due to age-related macular degeneration (AMD) or retinal arterial macroaneurysm (RAM).
Methods: The study design utilized a multicentric retrospective case series design of consecutive patients undergoing surgery between 2014 and 2019.
Results: A total of 65 eyes from 65 patients were included in the study. Surgery was performed after a mean period of 7.1 days. Displacement of MaH was achieved in 82% of the eyes. Mean best-corrected visual acuity (BCVA) improved from 20/500 to 20/125 at month(M)1 and M6 ( < 0.05). At M6, BCVA worsening was associated with an older age at diagnosis ( = 0.0002) and higher subretinal OCT elevation of MaH ( = 0.03). The use of treat and extend (TE) (OR = 16.7, = 0.001) and small MaH fundus size (OR = 0.64 and 0.74 for horizontal and vertical fundus size, < 0.05) were predictive of a higher likelihood of obtaining a countable BCVA at M1. Baseline BCVA was predictive of postoperative BCVA ( < 0.05). Retinal detachment and MaH recurrence occurred in 3% and 9.3% of cases at M6.
Conclusion: MaH surgery stabilizes or improves BCVA in 85% of cases. Younger age at diagnosis, better baseline BCVA figures, smaller subretinal MaH height and use of TE regime were predictive of the best postoperative outcomes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703651 | PMC |
| http://dx.doi.org/10.3390/jcm10245787 | DOI Listing |
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