Adversarial attacks on machine learning-based classifiers, along with defense mechanisms, have been widely studied in the context of single-label classification problems. In this paper, we shift the attention to multi-label classification, where the availability of domain knowledge on the relationships among the considered classes may offer a natural way to spot incoherent predictions, i.e., predictions associated to adversarial examples lying outside of the training data distribution. We explore this intuition in a framework in which first-order logic knowledge is converted into constraints and injected into a semi-supervised learning problem. Within this setting, the constrained classifier learns to fulfill the domain knowledge over the marginal distribution, and can naturally reject samples with incoherent predictions. Even though our method does not exploit any knowledge of attacks during training, our experimental analysis surprisingly unveils that domain-knowledge constraints can help detect adversarial examples effectively, especially if such constraints are not known to the attacker. We show how to implement an adaptive attack exploiting knowledge of the constraints and, in a specifically-designed setting, we provide experimental comparisons with popular state-of-the-art attacks. We believe that our approach may provide a significant step towards designing more robust multi-label classifiers.
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http://dx.doi.org/10.1109/TPAMI.2021.3137564 | DOI Listing |
Public Health Nutr
January 2025
Queensland Brain Institute, The University of Queensland, 79 Upland Road, St Lucia, QLD Australia 4067.
Objective: Early education and care (ECEC) is part of the everyday life of most children in developed economies presenting exceptional opportunity to support nutrition and ongoing food preferences. Yet, the degree to which such opportunity is captured in policy-driven assessment and quality ratings of ECEC services is unknown.
Design: Abductive thematic analysis was conducted, guided by key domains of knowledge in nutrition literature and examining identified themes within these domains.
Patient Prefer Adherence
January 2025
Division of Hypertension, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Introduction: Self-care practices are crucial for optimizing blood pressure control and are influenced by multilevel factors.
Objective: To examine the influences of multilevel factors on hypertension self-care practices among individuals with uncontrolled hypertension and to determine the relationship between hypertension self-care practices and blood pressure.
Methods: The study was conducted in primary, secondary, and tertiary care settings in Bangkok, selected for convenience, where individuals with uncontrolled hypertension were recruited using a convenience sampling method based on specific inclusion criteria.
Recent advancements in large language models (LLMs) like ChatGPT and LLaMA have shown significant potential in medical applications, but their effectiveness is limited by a lack of specialized medical knowledge due to general-domain training. In this study, we developed Me-LLaMA, a new family of open-source medical LLMs that uniquely integrate extensive domain-specific knowledge with robust instruction-following capabilities. Me-LLaMA comprises foundation models (Me-LLaMA 13B and 70B) and their chat-enhanced versions, developed through comprehensive continual pretraining and instruction tuning of LLaMA2 models using both biomedical literature and clinical notes.
View Article and Find Full Text PDFOrganisms with smaller genomes often perform multiple functions using one multi-subunit protein complex. The Silent Information Regulator complex (SIRc) carries out all of the core functions of heterochromatin. SIR complexes first drive the initiation and spreading of histone deacetylation in an iterative manner.
View Article and Find Full Text PDFElife
January 2025
John Innes Centre, Norwich Research Park, Norwich, United Kingdom.
Obligate parasites often trigger significant changes in their hosts to facilitate transmission to new hosts. The molecular mechanisms behind these extended phenotypes - where genetic information of one organism is manifested as traits in another - remain largely unclear. This study explores the role of the virulence protein SAP54, produced by parasitic phytoplasmas, in attracting leafhopper vectors.
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