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effects of aflatoxin B1 and benzo[]pyrene on the heart muscle of chicken embryos. | LitMetric

AI Article Synopsis

  • - The study aimed to assess how aflatoxin B1 (AFB1) and benzo[a]pyrene (BaP) affect the heart muscle in chicken embryos from the Ross 308 broiler line.
  • - Benzo[a]pyrene was injected on the 6th day of incubation in varying doses, while aflatoxin B1 was also injected into the yolk at different concentrations.
  • - Results show that even low doses of AFB1 and BaP during early development significantly altered various biochemical and hepatic parameters, indicating their toxic effects on embryonic development.

Article Abstract

The purpose of the present study was to evaluate the effects of aflatoxin B1 (AFB1) and benzo[a]pyrene (BaP) on the heart muscle of chicken embryos of the broiler line Ross 308. The benzo[a]pyrene in the organic oil solution was injected on the 6th day of the incubation in doses of: 0.1, 0.5, and 1 mg/kg weight of eggs; the aflatoxin B1 in the organic oil solution was injected on the 6th day of the incubation into the yolk in doses of 80, 120 and 240 ng/kg weight of eggs. Multiple biochemical and hepatic parameters have been observed, including sodium, potassium, chloride, cholesterol, uric acid, total proteins, aminotransferase aspartate, and aminotransferase alanine. A low dose of AFB1 and BaP administered during early embryonic development had a significant impact on chicken embryonic development, as demonstrated by alterations in biochemical, mineral, and hepatic parameters.

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Source
http://dx.doi.org/10.1080/10934529.2021.2011659DOI Listing

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