Clinical evaluation of two adult oxygenator systems in terms of mortality and major adverse events.

Purpose: The primary aim of this study was to examine the effects of two oxygenator systems on major adverse events and mortality.

Methods: A total of 181 consecutive patients undergoing coronary artery bypass grafting in our clinic were retrospectively analyzed. The patients were divided into two groups according to the oxygenator used: Group M, in which a Medtronic Affinity (Medtronic Operational Headquarters, Minneapolis, MN, USA) oxygenator was used, and Group S, in which a Sorin Inspire (Sorin Group Italia, Mirandola, Italy) oxygenator was used.

Results: Group S consisted of 89 patients, whereas Group M included 92 patients. No statistically significant differences were found between the two groups in terms of age ( = .112), weight ( = .465), body surface area ( = .956), or gender ( = .484). There was no statistically significant difference in hemorrhage on the first or second postoperative day ( = .318 and = .455, respectively). No statistically significant differences were observed in terms of red blood cell ( = .468), fresh frozen plasma ( = .116), or platelet concentrate transfusion ( = .212). Infections, wound complications, and delayed sternal closure were significantly more common in Group M ( = .006, = .023, and = .019, respectively). Extracorporeal membrane oxygenators and intra-aortic balloon pumps were required significantly more frequently in Group S ( = .025 and = .013, respectively). Major adverse events occurred in 16 (18%) patients in Group S and 14 (15.2%) patients in Group M ( = .382). Mortality was observed in six (6.7%) patients in Group S and three (3.3%) patients in Group M ( = .232). No statistically significant difference was found between the two groups in terms of length of hospital stay ( = .451).

Conclusion: The clinical outcomes of the two oxygenator systems, including mortality, major adverse events, hemorrhage, erythrocyte and platelet transfusions, and length of hospital stay, were similar.