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Prophylactic Irradiation for the Prevention of Heterotopic Ossification After Foot Amputation: A Case Series.
J Am Podiatr Med Assoc
January 2025
‡Department of Plastic Surgery, Medstar Georgetown University Hospital, Washington, DC.
Background: The formation of heterotopic ossification (HO) is a common complication after transosseous partial foot amputation. Development of HO in weightbearing and/or superficial areas can lead to increased pressures, which increases the likelihood of wound formation and pain. Current treatment modalities for HO of the foot include mechanical off-loading and surgical resection; however, prophylactic measures such as nonsteroidal anti-inflammatory drugs, bisphosphonates, and other medical therapies have been attempted previously with mixed efficacy.
View Article and Find Full Text PDFKnock-out mouse models and single particle ICP-MS reveal that SP-D and SP-A deficiency reduces agglomeration of inhaled gold nanoparticles in vivo without significant changes to overall lung clearance.
Nanotoxicology
January 2025
Infection, Inflammation and Repair, Faculty of Medicine, University of Southampton, Southampton, UK.
The role of surfactant proteins A and D (SP-A and SP-D) in lung clearance and translocation to secondary organs of inhaled nanoparticles was investigated by exposing SP-A and SP-D knockout (AKO and DKO) and wild type (WT) mice nose-only for 3 hours to an aerosol of 20 nm gold nanoparticles (AuNPs). Animals were euthanised at 0-, 1-, 7- and 28-days post-exposure. Analysis by inductively coupled plasma mass spectrometry (ICP-MS) of the liver and kidneys showed that extrapulmonary translocation was below the limits of detection.
View Article and Find Full Text PDFA linearly polarized AC-driven perovskite light emitting device with nanoscale metal contact.
Nanoscale
January 2025
Department of Photonics and Institute of Electro-Optical Engineering, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Electroluminescent (EL) devices consisting of a single metal-semiconductor contact and a gate effect structure have garnered significant attention in the field of perovskite light-emitting devices. This interest is largely due to the thermal stability of the active layer and the simplicity of the device structure. However, the application of these devices in large-area light-emitting applications is hindered by the inherently low carrier mobility in perovskite materials.
View Article and Find Full Text PDFA reconfigurable entanglement distribution network suitable for connecting multiple ground nodes with a satellite.
EPJ Quantum Technol
January 2025
Institute for Quantum Computing and Department of Physics & Astronomy, University of Waterloo, 200 University Ave W, Waterloo, N2L 3G1 Ontario Canada.
Satellite-based quantum communication channels are important for ultra-long distances. Given the short duration of a satellite pass, it can be challenging to efficiently connect multiple users of a city-wide network while the satellite is passing over that area. We propose a network with dual-functionality: during a brief satellite pass, the ground network is configured as a multipoint-to-point topology where all ground nodes establish entanglement with a satellite receiver.
View Article and Find Full Text PDFEvaluation of charge summing correction in CdTe-based photon-counting detectors for breast CT: performance metrics and image quality.
J Med Imaging (Bellingham)
January 2025
U.S. Food and Drug Administration, Office of Science and Engineering Labs, Division of Imaging, Diagnostics, and Software Reliability, Silver Spring, Maryland, United States.
Purpose: We evaluate the impact of charge summing correction on a cadmium telluride (CdTe)-based photon-counting detector in breast computed tomography (CT).
Approach: We employ a custom-built laboratory benchtop system using the X-THOR FX30 0.75-mm CdTe detector (Varex Imaging, Salt Lake City, Utah, United States) with a pixel pitch of 0.
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