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Cognitive Outcomes and Delirium After Cardiac Neurodevelopmental Program Implementation for Children With Congenital Heart Disease.
JAMA Netw Open
January 2025
Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora.
Importance: A recent advisory from the American Heart Association delineated the potential benefits of developmental care for hospitalized children with congenital heart disease (CHD) and a critical gap in research evaluating the association of such inpatient programs with neurodevelopmental outcomes.
Objective: To investigate associations between the Cardiac Inpatient Neurodevelopmental Care Optimization (CINCO) program interventions, delirium, and neurodevelopment in young children (newborn through age 2 years) hospitalized with CHD.
Design, Setting, And Participants: This cohort study used quality improvement data from inpatient cardiac units at a tertiary care children's hospital in the US.
DisCo P-ad: Distance-Correlation-Based -Value Adjustment Enhances Multiple Testing Corrections for Metabolomics.
Metabolites
January 2025
Department of Biostatistics & Informatics, Colorado School of Public Heath, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Background: Due to scientific advancements in high-throughput data production technologies, omics studies, such as genomics and metabolomics, often give rise to numerous measurements per sample/subject containing several noisy variables that potentially cloud the true signals relevant to the desired study outcome(s). Therefore, correcting for multiple testing is critical while performing any statistical test of significance to minimize the chances of false or missed discoveries. Such correction practice is commonplace in genome-wide association studies (GWAS) but is also becoming increasingly relevant to metabolome-wide association studies (MWAS).
View Article and Find Full Text PDFCorrection: Chen . β-Sitosterol Enhances Lung Epithelial Cell Permeability by Suppressing the NF-κB Signaling Pathway. Discovery Medicine. 2023; 35(179): 946-955.
Discov Med
January 2025
Department of Emergency Medicine, Jinling Hospital, Nanjing School of Clinical Medicine, Southern Medical University, 210002 Nanjing, Jiangsu, China.
Correction of Discovery Medicine 2023, 35 (179) https://www.discovmed.com/EN/10.
View Article and Find Full Text PDFMicrostructural and functional connectivity changes of decision-related brain networks in end-stage kidney disease patients undergoing peritoneal dialysis.
Kidney Res Clin Pract
January 2025
Department of Radiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
Background: We aimed to explore changes in decision-related brain microstructure, brain functional activities, and functional connectivity, and their correlations with cognitive function in end-stage kidney disease (ESKD) patients undergoing peritoneal dialysis (PD). Furthermore, the impact of dialysis on these changes was examined.
Methods: Thirty ESKD patients undergoing PD, 20 chronic kidney disease (CKD) stage 5 patients without dialysis (predialysis CKD stage 5), and 30 healthy controls (HC) were recruited for the study.
Author Correction: Layer-by-layer phase transformation in TiO revealed by machine-learning molecular dynamics simulations.
Nat Commun
January 2025
Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, China.
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