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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687494 | PMC |
| http://dx.doi.org/10.1590/0037-8682-0516-2021 | DOI Listing |
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Induction of ectosome formation by binding of phospholipases D from Loxosceles venoms to endothelial cell surface: Mechanism of interaction.
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Department of Cell Biology, Federal University of Paraná (UFPR), Curitiba 81530-900, Brazil. Electronic address:
Members of the phospholipase D (PLD) superfamily found in Loxosceles spider venoms are potent toxins with inflammatory and necrotizing activities. They degrade phospholipids in cell membranes, generating bioactive molecules that activate skin cells. These skin cells, in turn, activate leukocytes involved in dermonecrosis, characterized by aseptic coagulative necrosis.
View Article and Find Full Text PDFBinding of green tea epigallocatechin gallate to the arginine kinase active site from the brown recluse spider (): A potential synergist to chemical pesticides.
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spp. spiders can cause serious public health issues. Chemical control is commonly used, leading to health and environmental problems.
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The brown recluse spider () is endemic to the southcentral Midwest and the Southern United States. A bite from a brown recluse spider may result in symptoms that range from local skin necrosis to systemic complications such as acute haemolytic anaemia, disseminated intravascular coagulopathy, rhabdomyolysis and death. Although rare, systemic loxoscelism is a clinical diagnosis of exclusion that should be considered in a patient with acute autoimmune haemolytic anaemia.
View Article and Find Full Text PDFManagement of skin necrosis and wound dehiscence following brown recluse spider bite in the course of breast reconstruction: A case report.
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Article Synopsis
- Brown recluse spiders are a type of arachnid found in the U.S. that have venom causing serious health issues.
- Their venom can lead to severe skin damage and, in rare cases, systemic effects that may result in death within 24-48 hours.
- The text describes a specific case where a 44-year-old man experienced life-threatening complications from the spider's venom, necessitating emergency medical procedures.
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