AI Article Synopsis
- * A study analyzed 78 isolates from diseased pigs in Italy, revealing that nearly 60% of infections were linked to serotypes 1/2 and 9, with distinct clustering patterns among different sequence types.
- * Many serotype 9 isolates were found to be resistant to penicillin, raising concerns about treatment effectiveness and emphasizing the need for monitoring these S. suis strains in pigs for better disease management.
Article Abstract
Streptococcus suis is a pathogen associated with severe diseases in pigs and humans. Human infections have a zoonotic origin in pigs. To assess circulating strains, we characterized the serotypes, sequence types, and antimicrobial susceptibility of 78 S. suis isolates from diseased farmed pigs in Italy during 2017-2019. Almost 60% of infections were caused by serotypes 1/2 and 9. All but 1 of the serotype 2 and 1/2 isolates were confined to a single cluster, and serotype 9 isolates were distributed along the phylogenetic tree. Besides sequence type (ST) 1, the serotype 2 cluster included ST7, which caused severe human infections in China in 1998 and 2005. A large proportion of serotype 9 isolates, assigned to ST123, were resistant to penicillin. The emergence of this clone threatens the successful treatment of S. suis infection. Characterizing S. suis isolates from pigs will promote earlier detection of emerging clones.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714200 | PMC |
| http://dx.doi.org/10.3201/eid2801.210816 | DOI Listing |
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