AI Article Synopsis
- A study evaluated the effectiveness of COVID-19 vaccines in preventing hospitalizations among adults from March to August 2021, comparing hospitalized patients to non-infected controls.
- Vaccine effectiveness was found to be 96% for healthy individuals without chronic conditions and 83% for those with three or more medical conditions.
- The effectiveness of the vaccine did not significantly differ between younger adults (18-64 years) and older adults (65 years and above).
Article Abstract
Vaccine effectiveness (VE) against COVID-19 hospitalization was evaluated among immunocompetent adults (≥18 years) during March-August 2021 using a case-control design. Among 1669 hospitalized COVID-19 cases (11% fully vaccinated) and 1950 RT-PCR-negative controls (54% fully vaccinated), VE was 96% (95% confidence interval [CI], 93%-98%) among patients with no chronic medical conditions and 83% (95% CI, 76%-88%) among patients with ≥ 3 categories of conditions. VE was similar between those aged 18-64 years versus ≥65 years (P > .05). VE against severe COVID-19 was very high among adults without chronic conditions and lessened with increasing comorbidity burden.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113447 | PMC |
| http://dx.doi.org/10.1093/infdis/jiab619 | DOI Listing |
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