Leukocytoclastic vasculitis (LCV) is the vasculitis of small vessels. In this report, we describe a 38-year-old male patient who presented to our outpatient clinic with a 1-week history of rash on his lower extremities that had started 4 days after receiving the Pfizer-BioNTech SARS-CoV-2 vaccine. A diagnosis of LCV was made based on clinical and histopathological findings. The patient was treated with antihistamines and prednisolone, after which improvement was observed in the lesions. With this paper, we aim to raise awareness concerning the possibility of LCV development after COVID-19 vaccination.
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http://dx.doi.org/10.1111/dth.15279 | DOI Listing |
Chest
December 2024
Louisiana State University School of Medicine, New Orleans - Baton Rouge Regional Campus. Electronic address:
When an understanding of pathogenesis exists, skin lesions that have the appearance of blood in the skin can provide insight into the mechanisms leading to a systemic process that results in cutaneous manifestations. Of the vascular disturbances of the skin that occur in critically ill patients, some result from a non-hemorrhagic process while occurs represent bleeding into the skin. The lesions of livedo, petechiae, purpura, and ecchymoses can be approached from such a perspective.
View Article and Find Full Text PDFDermatol Online J
October 2024
Department of Dermatology, Fukushima Medical University, Fukushima, Japan.
Patients with granulomatosis with polyangiitis occasionally present with cutaneous manifestations, which are important clues for the early diagnosis. Although pyoderma gangrenosum-like ulcers are rarely observed, a unique case with unusual clinical features is presented herein. A 75-year-old woman with positive proteinase 3-antineutrophil cytoplasmic antibody (PR3-ANCA) repeatedly developed aseptic abscesses on the abdomen, buttock, lower legs, and forearms.
View Article and Find Full Text PDFCureus
November 2024
Paediatrics, NMC Specialty Hospital, Dubai, ARE.
Acute Haemorrhagic Oedema of Infancy (AHOI), also known as Acute Hemorrhagic Edema of Infancy (AHEI), is characterized by purpuric skin lesions, edema, and fever. It is classified as a form of cutaneous leukocytoclastic vasculitis. Clinically, AHOI presents with targetoid, purplish spots on the face and limbs, accompanied by the sudden onset of peripheral edema.
View Article and Find Full Text PDFArch Dermatol Res
December 2024
Department of Dermatology, Clinical Unit for Research Trials in Skin, Massachusetts General Hospital, 50 Staniford St, suite 240, Boston, MA, 02114, USA.
JACC Case Rep
November 2024
Internal Medicine, Ascension Saint John Hospital, Detroit, Michigan, USA.
Bacterial endocarditis presents as inflammation of the endocardium and valves of the 4 layers of the heart. The presentation and sequelae of bacterial endocarditis may vary and in certain circumstances may mimic rheumatologic disease. Antinuclear cytoplasmic antibody (ANCA)-positive bacterial endocarditis constitutes a special subgroup of bacterial endocarditis.
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