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Leptin levels in children with malnutrition. | LitMetric
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Leptin levels in children with malnutrition.

Resky Devi Akib Aminuddin Aminuddin Firdaus Hamid Prihantono Prihantono Burhanuddin Bahar Veni Hadju

Gac Sanit

Department of Midwifery, Graduate School, Hasanuddin University, Indonesia; Departement of Nutrition, Faculty of Medicine, Hasanuddin University, Indonesia; Department of Microbiology, Faculty of Medicine, Hasanuddin University, Indonesia; Department of Surgery, Faculty of Medicine, Hasanuddin University, Indonesia; Department of Nutrition, Faculty of Public Health, Hasanuddin University, Indonesia.

Published: January 2022

Objective: This study aimed at comparing serum levels of leptin in children with malnutrition and good nutritional status.

Method: This cross-sectional study included 41 participants consisting of 31 malnutrition, 10 well-nourished children aged between 36 and 60 months. Demographic data of participants were obtained utilizing a questionnaire. Nutritional status was determined by calculating the Z-score of body weight for age, height for age, and body weight for height indices using the WHO classification. Leptin levels were determined by ELISA (Enzyme-Linked Immunosorbent Assay) method.

Results: Median serum leptin level for malnutrition children were found to be lower, i.e., 9.23 (6.02-197.2) ng/mL compared to well-nourished children 30.95 (6.02-89.36) ng/mL.

Conclusion: Serum leptin levels can be used as indicators to assess nutritional status.

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 Source
http://dx.doi.org/10.1016/j.gaceta.2021.10.033DOI Listing

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