Road traffic accidents are a severe threat to human lives, particularly to vulnerable road users (VRUs) such as pedestrians causing premature deaths. Therefore, it is necessary to devise systems to prevent accidents in advance and respond proactively, using potential risky situations as one of the surrogate safety measurements. This study introduces a new concept of a pedestrian safety system that combines the field and the centralized processes. The system can warn of upcoming risks immediately in the field and improve the safety of risk-frequent areas by assessing the safety levels of roads without actual collisions. In particular, this study focuses on the latter by introducing a new analytical framework for a crosswalk safety assessment with various behaviors of vehicles/pedestrians and environmental features. We obtain these behavioral features from actual traffic video footages in the city with complete automatic processing. The proposed framework mainly analyzes these behaviors in multi-dimensional perspectives by constructing a data cube structure, which combines the Long Short-Term Memory (LSTM)-based predictive collision risk (PCR) estimation model and the on-line analytical processing (OLAP) operations. From the PCR estimation model, we categorize the severity of risks as four levels; "relatively safe," "caution," "warning," and "danger," and apply the proposed framework to assess the crosswalk safety with behavioral features. With the proposed framework, the various descriptive results are harvested, but we aim at conducting analysis based on two scenarios in our analytic experiments; the movement patterns of vehicles and pedestrians by road environment and the relationships between risk levels and car speeds. Consequently, the proposed framework can support decision-makers (e.g., urban planners, safety administrators) by providing the valuable information to improve pedestrian safety for future accidents, and it can help us better understand cars' and pedestrians' proactive behavior near the crosswalks. In order to confirm the feasibility and applicability of the proposed framework, we implement and apply it to actual operating CCTVs in Osan City, Republic of Korea.
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http://dx.doi.org/10.1016/j.aap.2021.106539 | DOI Listing |
J Cheminform
January 2025
Department of Intelligent Electronics and Computer Engineering, Chonnam National University, Gwangju, Republic of Korea.
The human ether-a-go-go-related gene (hERG) channel plays a critical role in the electrical activity of the heart, and its blockers can cause serious cardiotoxic effects. Thus, screening for hERG channel blockers is a crucial step in the drug development process. Many in silico models have been developed to predict hERG blockers, which can efficiently save time and resources.
View Article and Find Full Text PDFOrphanet J Rare Dis
January 2025
Laboratory of Neurogenetics and Molecular Medicine, Center for Genomic Sciences in Medicine, Institut de Recerca Sant Joan de Déu, Únicas SJD Center, Hospital Sant Joan de Déu, Barcelona, Spain.
Background: Rare diseases (RDs) are a heterogeneous group of complex and low-prevalence conditions in which the time to establish a definitive diagnosis is often too long. In addition, for most RDs, few to no treatments are available and it is often difficult to find a specialized care team.
Objectives: The project "acERca las enfermedades raras" (in English: "bringing RDs closer") is an initiative primary designed to generate a consensus by a multidisciplinary group of experts to detect the strengths and weaknesses in the public healthcare system concerning the comprehensive care of persons living with a RD (PLWRD) in the region of Catalonia, Spain, where a Network of Clinical Expert Units (Xarxa d'Unitats de Expertesa Clínica or XUEC) was created and is being implemented since 2015.
BMC Psychiatry
January 2025
West China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu, China.
The current DSM-oriented diagnostic paradigm has introduced the issue of heterogeneity, as it fails to account for the identification of the neurological processes underlying mental illnesses, which affects the precision of treatment. The Research Domain Criteria (RDoC) framework serves as a recognized approach to addressing this heterogeneity, and several assessment and translation techniques have been proposed. Among these methods, transforming RDoC scores from electronic medical records (EMR) using Natural Language Processing (NLP) has emerged as a suitable technique, demonstrating clinical effectiveness.
View Article and Find Full Text PDFInternet of Things (IoT) is one of the most important emerging technologies that supports Metaverse integrating process, by enabling smooth data transfer among physical and virtual domains. Integrating sensor devices, wearables, and smart gadgets into Metaverse environment enables IoT to deepen interactions and enhance immersion, both crucial for a completely integrated, data-driven Metaverse. Nevertheless, because IoT devices are often built with minimal hardware and are connected to the Internet, they are highly susceptible to different types of cyberattacks, presenting a significant security problem for maintaining a secure infrastructure.
View Article and Find Full Text PDFSci Rep
January 2025
School of Information Engineering, Tianjin University of Commerce, Tianjin, China.
Deep learning is a double-edged sword. The powerful feature learning ability of deep models can effectively improve classification accuracy. Still, when the training samples for each class are limited, it will not only face the problem of overfitting but also significantly affect the classification result.
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