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http://dx.doi.org/10.1002/psp4.12756 | DOI Listing |
Int J Mol Sci
December 2024
Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
The global issue of aging populations has become increasingly prominent, thus the research and development for anti-aging therapies to assure longevity as well as to ameliorate age-related complications is put high on the agenda. The young humoral milieu has been substantiated to impart youthful characteristics to aged cells or organs. Extracellular vesicles (EVs) are a heterogeneous group of cell-derived membrane-limited structures that serve as couriers of proteins and genetic material to regulate intercellular communication.
View Article and Find Full Text PDFJ Neurophysiol
January 2025
KU Leuven, Department of Movement Sciences, B-3000 Leuven, Belgium.
In motor adaptation, learning is thought to rely on a combination of several processes. Two of these are implicit learning (incidental updating of the movement due to sensory prediction error) and explicit learning (intentional adjustment to reduce target error). The explicit component is thought to be fast adapting, while the implicit one is slow.
View Article and Find Full Text PDFBackground: Long QT Syndrome Type-2 (LQT2) is due to loss-of-function variants. encodes K 11.1 that forms a delayed-rectifier potassium channel in the brain and heart.
View Article and Find Full Text PDFExp Anim
December 2024
Immunology and Allergy Laboratory, Immunology Unit, Department of Medical Innovations, Osaka Research Center for Drug Discovery, Otsuka Pharmaceutical Co., Ltd.
Atopic dermatitis (AD) is a chronic skin disease that causes itching and is characterized by recurrent flares and remissions. The interactions among type 2 inflammation, skin barrier dysfunction, and pruritus play important roles in the pathogenesis of AD. AD symptoms persist for a long period; thus, it is desirable to have disease models that reproduce a prolonged AD-like phenotype.
View Article and Find Full Text PDFLipids Health Dis
December 2024
Physical Education College, Hebei Normal University, Shijiazhuang, China.
Background: High-intensity interval training (HIT) does not burn fat during exercise. However, it significantly reduces visceral adipose after long-term training. The underlying mechanism may be related to the elevation of fat consumption during the post-exercise recovery period, which is regulated by the hypothalamus-adipose axis.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!