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| http://dx.doi.org/10.1177/15357597211036815 | DOI Listing |
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Multimodal physiological correlates of dyspnea ratings during breath-holding in healthy humans.
Eur J Appl Physiol
October 2024
APHP Sorbonne Université, INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale Et Clinique, 47-83 Boulevard de L'Hôpital, 75013, Paris, France.
Introduction And Objectives: Dyspnea is associated with fear and intense suffering and is often assessed using visual analog scales (VAS) or numerical rating scales (NRS). However, the physiological correlates of such ratings are not well known. Using the voluntary breath-holding model of induced dyspnea, we studied healthy volunteers to investigate the temporal relationship between dyspnea, the neural drive to breathe assessed in terms of involuntary thoracoabdominal movements (ITMs) and neurovegetative responses.
View Article and Find Full Text PDFRefractory Obstructive Sleep Apnea Secondary to Vagal Nerve Stimulation.
Cureus
August 2024
Department of Neurology, Division of Pulmonary and Critical Care, Center for Sleep Medicine, Mayo Clinic, Rochester, USA.
Vagal nerve stimulator (VNS) devices are commonly used as a non-pharmacologic option for improved seizure control in patients with refractory epilepsy. However, a side effect associated with VNS device placement includes sleep-disordered breathing, which is complicated by the fact that a significant minority of patients with epilepsy have sleep-disordered breathing. We describe a patient with iatrogenically worsened refractory obstructive sleep apnea (OSA) secondary to VNS device placement, which resolved upon turning off the VNS device.
View Article and Find Full Text PDFProspective Evaluation of a Modified Apnea Test in Brain Death Candidates that Does Not Require Disconnection from the Ventilator.
Neurocrit Care
December 2024
Department of Neurology and Clinical Neurophysiology (Klinik für Neurologie und Neurophysiologie), Freiburg University Medical Center (Universitätsklinikum Freiburg), Breisacherstr. 64, 79106, Freiburg, Germany.
Background: The apnea test (AT) is an important component in the determination of brain death/death by neurologic criteria (BD/DNC) and often entails disconnecting the patient from the ventilator followed by tracheal oxygen insufflation to ensure adequate oxygenation. To rate the test as positive, most international guidelines state that a lack of spontaneous breathing must be demonstrated when the arterial partial pressure of carbon dioxide (PaCO) ≥ 60 mm Hg. However, the loss of positive end-expiratory pressure that is associated with disconnection from the ventilator may cause rapid desaturation.
View Article and Find Full Text PDFPhenotyping OSA: Conceptualization and Implications for Treatment with Mandibular Advancement Devices.
Dent Clin North Am
July 2024
Unidade de Sono, Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal; Centro Europeu do Sono, Lisboa, Portugal; Clínica Universitária de Cardiologia, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal. Electronic address:
Obstructive Sleep Apnea (OSA) is a common medical disorder and the most impacting sleep disturbance. OSA derive from the narrowing of the upper airway during sleep, which result in recurrent episodes of ventilatory disturbances expressed by an increased airflow resistance (flow limitation and hypopneas) and often an absence of ventilation (apneas). The high heterogeneity in the clinical picture of OSA turns diagnostic and treatment challenging.
View Article and Find Full Text PDFThe Role of Telemedicine in Children with Obstructive Sleep Apnea Syndrome (OSAS): A Review of the Literature.
J Clin Med
April 2024
Pediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
The advent of telemedicine marked a significant turning point in the healthcare landscape, introducing a revolutionary approach to the delivery of medical care. Digital technologies easily connect health professionals and patients, overcoming geographical and temporal barriers. Telemedicine has been used for sleep disorders including obstructive sleep apnea syndrome (OSAS) since the mid-1990s.
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