[Gastric mucosal calcinosis].

Ann Pathol

Service d'anatomopathologie, CHU Amiens Picardie, Site Nord (Hôpital Nord), 1, place Victor-Pauchet, 80054 Amiens cedex 1, France.

Published: January 2022

The gastric mucosal calcinosis is a benign condition corresponding to calcium deposits in the gastric mucosa. A 39-year-old women, with an history of transplantation, transplant rejection and hemodialysis, treated with corticosteroids and calcium/phosphoremic supplements, had chronic diarrhea. Gastroduodenal fibroscopy found an atypical atrophic gastritis appearance with small focal whitish deposits in the gastric mucosa. Histological examination revealed brown and gray-bluish crystalline deposits in superficial chorion, stained by Von Kossa, leading to a diagnosis of gastric mucosal calcinosis. This lesion can be categorized as systemic, dystrophic, iatrogenic and idiopathic. In our observation, gastric mucosal calcinosis was probably mixed, linked to renal disorders, and mainly to exogenous phosphocalcic drug intakes. The gastric mucosal calcinosis is commonly found  in kidney transplant patients reaching a frequency of 15 to 29%.

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http://dx.doi.org/10.1016/j.annpat.2021.06.009DOI Listing

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