A chemical investigation on the 90% EtOH extract of the fruiting bodies of led to the isolation of three new lanostane triterpenoids, designated as 25-methoxy-11-oxo-ganoderiol D (), 3-oxo-25-methoxy-24,26-dihydroxy-lanosta-7,9(11)-diene (), and 3-acetyloxy-lucidone H (). Structural elucidation of all the compounds were performed by spectral methods such as 1 D and 2 D (HH COSY, HMQC, and HMBC) NMR spectroscopy. All the triterpenoids were evaluated for their antimicrobial activities against six pathogenic microorganisms. Compounds and exhibited some activities against three Gram positive bacteria with MIC values less than 60 μg/ml.

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http://dx.doi.org/10.1080/10286020.2021.2017899DOI Listing

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