This work evaluated the genetic damage in descendants of male pupae of Aedes (Stegomyia) aegypti (Diptera: Culicidae) separately exposed to 20, 30, and 40 Gy of gamma radiation in the context of Sterile Insect Technique (SIT). Despite the transmission of the dominant lethal mutation, the employed dose levels did not promote a marked reduction in adult mosquito emergence and fertility. This study emphasized that semi-sterilizing doses < 50 Gy for SIT of Aedes aegypti are not recommended.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.actatropica.2021.106284 | DOI Listing |
Int J Biol Macromol
December 2024
Radiation Biology Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt.
Globally, traumatic injuries and severe hemorrhagic wounds resulting from natural disasters, wars, traffic accidents, and operation rooms, especially during birth, are among the most difficult humanitarian and economic problems. Thus, the priority in emergency medical treatment is reducing unexpected blood loss, which can significantly influence a patient's rescue and recovery speed. For the immediate cessation of bleeding in severe hemorrhagic wounds and to speed up their healing, environmentally friendly γ-ionizing irradiation technology was used to develop innovative natural-based hydrogels impregnated with traditional medicinal plant extracts (MPE) with proven hemostatic and bactericidal potential as potential dressings for hemostasis, infection control, and wound healing.
View Article and Find Full Text PDFJ Environ Radioact
December 2024
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, DHHS, NIH, Bethesda, MD, 20892-9778, USA; Faculty of Health and Life Sciences, Oxford Brookes University, Headington Campus, Oxford, OX3 0BP, UK. Electronic address:
We investigate methods that improve the estimation of indoor gamma ray dose rates at locations where measurements had not been made. These new predictions use a greater range of modelling techniques and larger variety of explanatory variables than our previous examinations of this subject. Specifically, we now employ three types of machine learning models in addition to the geostatistical, nearest neighbour and other earlier models.
View Article and Find Full Text PDFMalays J Pathol
December 2024
Universiti Tunku Abdul Rahman, M. Kandiah Faculty of Medicine and Health Sciences, Department of Pre-clinical Sciences, Bandar Sungai Long, 43000, Kajang, Selangor, Malaysia.
Introduction: The current first-line therapy for nasopharyngeal carcinoma (NPC) is often associated with long-term complications. Oncolytic measles virus (MV) therapy offers a promising alternative to cancer therapy. This study aims to investigate the efficacy of MV in killing NPC cells in vitro, both with or without resistance to radiation and drug therapy.
View Article and Find Full Text PDFBMC Palliat Care
December 2024
The Palliative Care Center, Päijät-Häme Wellbeing Services County, Lahti, Finland.
Background: Studies show that hospital deaths bring significant health care costs, and the involvement of specialized palliative care can help to reduce these costs. The aim of this retrospective registry-based study was to evaluate end-of-life hospital costs in patients dying in a university hospital oncology ward, with or without specialized palliative outpatient clinic contact at any timepoint.
Methods: The study population consists of all patients who died in the Kuopio University Hospital oncology ward in the years 2012-2018 (n = 457).
In Saccharomyces cerevisiae cells, the bulk of mitochondrial DNA (mtDNA) replication is mediated by the replicative high-fidelity DNA polymerase γ. However, upon UV irradiation low-fidelity translesion polymerases: Polη, Polζ and Rev1, participate in an error-free replicative bypass of UV-induced lesions in mtDNA. We analysed how translesion polymerases could function in mitochondria.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!