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Plant-Based Systems for Vaccine Production. | LitMetric

Plant-Based Systems for Vaccine Production.

Methods Mol Biol

Department of Biotechnology, University of Verona, Verona, Italy.

Published: January 2022

Plant systems have been used as biofactories to produce recombinant proteins since 1983. The huge amount of data, collected so far in this framework, suggests that plants display several key advantages over existing traditional platforms when they are intended for therapeutic uses, including safety, scalability, and the speed in obtaining the final product.Here, we describe a method that could be applied for the expression and production of a candidate subunit vaccine in Nicotiana benthamiana plants by transient expression, defining all the protocols starting from plant cultivation to target recombinant protein purification.

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http://dx.doi.org/10.1007/978-1-0716-1892-9_6DOI Listing

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