Cases of extensively drug-resistant (XDR) typhoid fever have been reported in the United States among patients who did not travel internationally. Clinicians should consider if and where the patient traveled when selecting empiric treatment for typhoid fever. XDR typhoid fever should be treated with a carbapenem, azithromycin, or both.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669042PMC
http://dx.doi.org/10.1093/ofid/ofab572DOI Listing

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