Increased foot strike variability during turning in Parkinson's disease patients with freezing of gait.

Gait Posture

Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Center for Translational Neuroscience, University of Arkansas for Medical Sciences, Little Rock, AR, USA. Electronic address:

Published: February 2022

Background: Turning is a common trigger for freezing episodes in patients with Parkinson's disease (PD). Freezing during turning can lead to falls and fractures and decreased quality of life.

Research Question: Does foot-strike contact variability also increase during turning, as previously reported in straight gait in PD patients with Freezing of Gait (FOG)?

Methods: Subjects were instructed to walk on a gait mat, making "normal pivot" (180°) turns at each end. ProtoKinetics Movement Analysis Software (PKMAS) software was used for analysis. Video recordings and foot-pressure-prints were studied to identify and define turn segments. Spatiotemporal gait and turn measures were then determined only for the turn segments. A movement disorders neurologist determined clinical freezes.

Results: 100 subjects (28 controls, 38 noFOG and 34 FOG) were included. Compared to non-freezers (noFOG), FOG subjects had a smaller foot-strike during turning (a measure of completeness of foot contact with the mat) and increased foot-strike variability. FOG subjects also had a shorter stride-length, slower stride-velocity, and greater swing phase time and percentage during turns. After adjusting for turn direction, inner/outer leg dynamics showed heavier inner leg footsteps in FOG subjects. 38% of FOG subjects experienced freezes during turning. 69% of freezes occurred during the middle third of the turn. Turn-freezers had more severe spatiotemporal gait deficits.

Significance: Developing targeted therapies to retrain subjects to plant their whole foot on the ground with more consistency could help decrease episodes of freezing of gait.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109154PMC
http://dx.doi.org/10.1016/j.gaitpost.2021.12.012DOI Listing

Publication Analysis

Top Keywords

fog subjects
16
freezing gait
12
parkinson's disease
8
patients freezing
8
turn segments
8
spatiotemporal gait
8
nofog fog
8
gait
7
subjects
7
turning
6

Similar Publications

Background: It is known that COVID-19 causes brain damage in the acute phase and leads to neurological complications such as dementia and brain fog in the chronic phase. Many factors have been implicated in these complications, including glymphatic system disorders, small vessel disease, and widespread inflammation. Peak width of skeletonized mean diffusivity (PSMD) is a sensitive biomarker for SVD, while the diffusion tensor image analysis along the perivascular space (DTI-ALPS) measures glymphatic system function.

View Article and Find Full Text PDF

The rapid advancements in medical technology throughout the past two decades have greatly enhanced life expectancy, ushering in an era where ageing populations are thriving. However, this demographic shift has also brought attention to age-related issues, particularly neurological disorders. This paper addresses the challenges posed by one such neurological disorder Parkinson's disease (PD), with a focus on the debilitating symptom of Freezing of Gait (FoG).

View Article and Find Full Text PDF

Introduction: The rise of artificial intelligence (AI), including generative chatbots like ChatGPT (OpenAI, San Francisco, CA, USA), has revolutionized many fields, including healthcare. Patients have gained the ability to prompt chatbots to generate purportedly accurate and individualized healthcare content. This study analyzed the readability and quality of answers to Achilles tendon rupture questions from six generative AI chatbots to evaluate and distinguish their potential as patient education resources.

View Article and Find Full Text PDF

Accurate and efficient insulator maintenance: A DETR algorithm for drone imagery.

PLoS One

February 2025

Faculty of Computer Science and Information Technology, Universiti Malaya, Kuala Lumpur, Malaysia.

With the increasing demand for electricity, the safety and stability of power grids become paramount, highlighting the critical need for effective maintenance and inspection. Insulators, integral to power grid maintenance as protective devices on outdoor high-altitude conductors, are often subject to suboptimal image quality during drone-based inspections due to adverse weather conditions such as rain, snow, fog, and the challenges posed by sunlight, high-speed movement, and long-distance imaging. To address these challenges and achieve a more accurate inspection system, this manuscript introduces an insulator defect detection algorithm tailored for the low-quality images collected by drone-based imaging systems.

View Article and Find Full Text PDF

Hypothyroidism, also known as an underactive thyroid, is an endocrine condition in which the thyroid gland does not produce enough thyroid hormones to meet the body's needs. Hypothyroidism can develop slowly over time and cause a variety of symptoms, including fatigue, muscle weakness and stiffness, cold intolerance, brain fog, anxiety, limb numbness or tingling sensation, and palpitations. The following case describes a 32-year-old female who presented with anxiety-like symptoms closely resembling the classic symptomatology of hypothyroidism.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!