Franz Tappeiner (1816-1902) was an Austrian scientist: physician and anthropologist. He studied medicine at the universities of Prague and Padua, and completed his medical education receiving his doctorate in 1843 in Vienna. Tappeiner investigated the transmission of pulmonary tuberculosis in animal models and he dealt with public health, in particular Merano's welfare and public health regulations. In 1877, in the Anatomical and Pathological Institute of Munich led by the German pathologist Ludwig von Buhl (1816-1880), Tappeiner studied the transmission of pulmonary tuberculosis in animal models, by exposing dogs to sputum of phthisic patients affected by this disease. He was able to show that phthisis and tuberculosis were the same disease, which could be spread through inhalation. These studies were pioneering and preceded by 10 years the discovery of the tuberculosis bacillus by Robert Koch (1843-1910) in 1882. The research activities of Tappeiner were focal in tracking the future path for Koch's discovery and represent milestones in the history of tuberculosis.
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http://dx.doi.org/10.1016/j.tube.2021.102160 | DOI Listing |
J Clin Med
January 2025
Innovation, Research and Teaching Service (SABES-ASDAA), Teaching Hospital of the Paracelsus Medical Private University (PMU), 39100 Bolzano, Italy.
: This study investigates the potential of artificial intelligence (AI), specifically large language models (LLMs) like ChatGPT, to enhance decision support in diagnosing epilepsy. AI tools can improve diagnostic accuracy, efficiency, and decision-making speed. The aim of this study was to compare the level of agreement in epilepsy diagnosis between human experts (epileptologists) and AI (ChatGPT), using the 2014 International League Against Epilepsy (ILAE) criteria, and to identify potential predictors of diagnostic errors made by ChatGPT.
View Article and Find Full Text PDFJ Pers Med
January 2025
Unit of Pediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
: Femoral neck fractures are rare but serious injuries in children and adolescents, often resulting from high-energy trauma and prone to complications like avascular necrosis (AVN) and nonunion. Even rarer is the development of slipped capital femoral epiphysis (SCFE) following femoral neck fracture, which presents unique diagnostic and treatment challenges. SCFE can destabilize the femoral head, with severe cases requiring complex surgical interventions.
View Article and Find Full Text PDFAm Heart J
December 2024
Department of Cardiology, San Maurizio Regional Hospital, Bolzano, Italy.
Background: Cardiac resynchronization therapy (CRT) is a cornerstone treatment for heart failure, yet the optimal pacing mode remains uncertain. This study investigates the impact of DDDR (rate-adaptive atrial support) versus VDD pacing modes on functional capacity and echocardiographic outcomes in patients with CRT-defibrillators.
Methods: In a multicenter, double-blind, crossover trial, 26 sinus rhythm patients undergoing CRT-defibrillator implantation were randomized to DDDR at 60 beats-per-minute or VDD at 30 beats-per-minute.
Clin Neurophysiol Pract
October 2024
Department of Engineering for Innovation Medicine, University of Verona, Italy.
Myoclonus has multiple clinical manifestations and heterogeneous generators and etiologies, encompassing a spectrum of disorders and even physiological events. This paper, developed from a teaching course conducted by the Neurophysiology Commission of the Italian League against Epilepsy, aims to delineate the main types of myoclonus, identify potential underlying neurological disorders, outline diagnostic procedures, elucidate pathophysiological mechanisms, and discuss appropriate treatments. Neurophysiological techniques play a crucial role in accurately classifying myoclonic phenomena, by means of simple methods such as EEG plus polymyography (EEG + Polymyography), evoked potentials, examination of long-loop reflexes, and often more complex protocols to study intra-cortical inhibition-facilitation In clinical practice, EEG + Polymyography often represents the first step to identify myoclonus, acquire signals for off-line studies and plan the diagnostic work-up.
View Article and Find Full Text PDFNeurol Sci
January 2025
Department of Neurology, Hospital of Merano (SABES-ASDAA), Franz Tappeiner Hospital, Via Rossini, 5, 39012, Merano, Italy.
Objectives: In March 2020, the World Health Organization declared the coronavirus-related disease SARS-CoV-2 infection pandemic. Italy was one of the most affected countries and managed the emergency also by a health care reorganization.
Methods: The Education and Career Development Task Force of the Young Epilepsy Section-Italy (YES-I) designed a survey to assess the impact of the pandemic on the training and work of young epileptologists (< 40 years).
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