Congenital red hair heterochromia in the background of blond scalp hair.

Pediatr Dermatol

Department of Dermatology, Loma Linda University, Loma Linda, California, USA.

Published: January 2022

We report a case of isolated patchy red hair heterochromia of the scalp in a healthy 6-year-old boy. Isolated patchy scalp hair heterochromia is the presence of two or more colors of hair in the same individual, thought to be due to genetic mosaicism although no specific etiology has been widely accepted. We have outlined a basic approach to diagnosing different types of heterochromia for clinical application.

Download full-text PDF

Source
http://dx.doi.org/10.1111/pde.14886DOI Listing

Publication Analysis

Top Keywords

hair heterochromia
12
red hair
8
scalp hair
8
isolated patchy
8
hair
5
congenital red
4
heterochromia
4
heterochromia background
4
background blond
4
blond scalp
4

Similar Publications

Article Synopsis
  • Waardenburg syndrome (WS) is a rare congenital disorder mainly inherited in an autosomal dominant manner, exhibiting incomplete penetrance and diverse clinical presentations within the same family.
  • Key features include facial abnormalities, skin hypopigmentation, heterochromia iridis, and conductive deafness, with four distinct subtypes characterized by specific symptoms.
  • Type 4, the rarest subtype associated with Hirschsprung disease, shows symptoms like white forelock and hearing loss, emphasizing the need for genetic counseling and awareness for proper diagnosis and management.
View Article and Find Full Text PDF

Introduction: Mitogen-activated extracellular signal-regulated kinase (MEK) inhibitors are in use for several indications for adults and children. Cutaneous toxicities are among the most common adverse effects. We aimed to describe the spectrum of cutaneous adverse events, its frequency, and severity in a cohort of pediatric patients.

View Article and Find Full Text PDF

Hair heterochromia may be caused by different mechanisms. At clinical work, we found a Chinese boy whose hair colour gradually turned to red. We record the diagnosis and treatment process and follow-up situation, finally find that altered hair colour phenotype is due to MC1R genetic mutations, rather than zinc deficiency.

View Article and Find Full Text PDF

Background: Waardenburg syndrome (WS) is a rare genetic disorder characterized by varying degrees of sensorineural hearing loss and accumulated pigmentation in the skin, hair and iris. The syndrome is classified into four types (WS1, WS2, WS3, and WS4), each with different clinical phenotypes and underlying genetic causes. The aim of this study was to identify the pathogenic variant in a Chinese family with Waardenburg syndrome type IV.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!