Ropivacaine:An Unusual Cause of Neuroleptic Malignant-Like Syndrome.

Eur J Case Rep Intern Med

Serviço de Urgência Geral, Hospital de Braga, Braga, Portugal.

Published: November 2021

Unlabelled: Ropivacaine is commonly used for post-operative pain management. We describe a case of neuroleptic malignant-like syndrome in a woman administered ropivacaine delivered using a drug infusion balloon. The presenting symptoms were confusion, agitation and fever. Blood analysis showed elevated C-reactive protein, leucocytosis and increased creatine phosphokinase. As intoxication was suspected, ropivacaine was suspended and the patient gradually improved. Possible leakage of ropivacaine into the intrathecal space may have resulted in central nervous system toxicity.

Learning Points: It is important to be aware of the secondary effects of common drugs.The differential diagnosis should always include side effects and drug interactions.Intoxication can lead to poor outcomes, so early recognition is key.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667995PMC
http://dx.doi.org/10.12890/2021_002971DOI Listing

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