Glaucoma is a major threatening cause, in which it affects the optical nerve to lead to a permanent blindness to individuals. The major causes of Glaucoma are high pressure to eyes, family history, irregular sleeping habits, and so on. These kinds of causes lead to Glaucoma easily, and the effect of such disease leads to heavy damage to the internal optic nervous system and the affected person will get permanent blindness within few months. The major problem with this disease is that it is incurable; however, the affection stages can be reduced and the same level of effect as that for the long period can be maintained but this is possible only in the earlier stages of identification. This Glaucoma causes structural effect to the eye ball and it is complex to estimate the cause during regular diagnosis. In medical terms, the Cup to Disc Ratio (CDR) is minimized to the Glaucoma patients suddenly and leads to harmful damage to one's eye in severe manner. The general way to identify the Glaucoma is to take Optical Coherence Tomography (OCT) test, in which it captures the uncovered portion of eye ball (backside) and it is an efficient way to visualize diverse portions of eyes with optical nerve visibility shown clearly. The OCT images are mainly used to identify the diseases like Glaucoma with proper and robust accuracy levels. In this work, a new methodology is introduced to identify the Glaucoma in earlier stages, called Depth Optimized Machine Learning Strategy (DOMLS), in which it adapts the new optimization logic called Modified K-Means Optimization Logic (MkMOL) to provide best accuracy in results, and the proposed approach assures the accuracy level of more than 96.2% with least error rate of 0.002%. This paper focuses on the identification of early stage of Glaucoma and provides an efficient solution to people in case of effect by such disease using OCT images. The exact position pointed out is handled by using Region of Interest- (ROI-) based optical region selection, in which it is easy to point the optical cup (OC) and optical disc (OD). The proposed algorithm of DOMLS proves the accuracy levels in estimation of Glaucoma and the practical proofs are shown in the Result and Discussions section in a clear manner.
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http://dx.doi.org/10.1155/2021/5709257 | DOI Listing |
J Glaucoma
March 2025
Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil.
Prcis: Patients with clinically uncontrolled open-angle glaucoma submitted to isolated gonioscopy-assisted transluminal trabeculotomy or combined with phacoemulsification not only achieved low mean IOPs, but also demonstrated stable IOP patterns during a 24-month follow-up.
Purpose: To assess the impact of gonioscopy-assisted transluminal trabeculotomy (GATT) on long term intraocular pressure (IOP) variation.
Patients And Methods: An unicentric retrospective study including 169 consecutive patients who had undergone standalone GATT or combined with phacoemulsification (PHACOGATT) due to clinically uncontrolled open-angle glaucoma, with at least 12 months of follow-up was conducted.
J Glaucoma
March 2025
Department of Ophthalmology, Harvey and Bernice Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR.
Precis: In this prospective multicenter study, eyes with primary congenital glaucoma exhibited lower retinal vascular parameters compared to healthy controls, as assessed by optical coherence tomography angiography fractal dimension analysis.
Purpose: To study the retino-choroidal peripapillary microvascular pattern in primary congenital glaucoma (PCG) using fractal dimension (FD) analysis and compare it to healthy controls.
Methods: This was a prospective multicenter comparative study.
J Glaucoma
March 2025
Smt. Jadhavbai Nathmal Singhvee Glaucoma Services Medical Research Foundation, Sankara Nethralaya, Chennai.
Precis: Visual fields in glaucoma significantly progressed during the COVID-19 pandemic, likely due to reduced compliance and lack of availability of medication.
Purpose: To study the impact of the COVID-19 pandemic on the rate of visual field progression in glaucoma and to validate the factors affecting progression.
Methods: This hospital based prospective cohort study included patients diagnosed with primary open angle glaucoma, primary angle closure glaucoma and ocular hypertension who fulfilled the eligibility criteria.
J Glaucoma
March 2025
Department of Ophthalmology, National University Hospital, National University Health System.
Prcis: In this retrospective cohort study, the 1-year cumulative probability of failure was comparable, achieving 52.20% in the phacoemulsification-iStent inject W (phaco/iStent) group and 47.80% in the phacoemulsification-micropulse transscleral laser therapy (phaco/MPTLT) group (P=0.
View Article and Find Full Text PDFJ Glaucoma
March 2025
Department of Ophthalmology, University of Washington, Seattle, WA, USA.
Precis: Higher Social Vulnerability Index scores, limited-English proficiency and retirement/disability status were associated with lower odds of completing one visual field and optical coherence tomography/year in glaucoma patients.
Purpose: To assess the correlation between sociodemographic factors and the Social Vulnerability Index to the likelihood of not receiving one visual field testing and one retinal nerve fiber layer optical coherence tomography test per year.
Methods: Patient records with glaucoma living in Washington state from a single academic institution (2014-2021) were reviewed.
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